Micro-fluidic spectral waveguide structure for regulating light sensing gene

Abstract

The invention relates to the technical field of optical waveguide of fluids and particularly relates to a micro-fluidic spectral waveguide structure for regulating a light sensing gene. The structure comprises a spectral waveguide chip, an electrode detecting and recording sheet and a cell culture runner, wherein the cell culture runner is arranged at the light outlet of the spectral waveguide chip which is in a dividing light-splitting structure for dividing stimulating light into multiple lights; the stimulating light is used for stimulating cells in the cell culture runner; the electrode detecting and recording sheet is used for collecting response signals of cells. By adopting the dividing light-splitting structure provided by the invention, an array light source can be generated to achieve independent and high-precision fixed-point stimulation and culture of light sensitive nerve cells, thus a multi-point small light source stimulates every nerve cell in a nerve network. The quantity of dot matrixes of laser outlet points can be optimized according to demand. The structure has the advantages of being centralized in intensity of light source, small in transmitting area, adjustable in wavelength and skillful and simple in structural design.

Description

technical field [0001] The invention relates to the field of fluid optical waveguide technology, in particular to a microfluidic light-splitting waveguide structure for light-sensing gene regulation. Background technique [0002] The current technology for studying light-sensing genes is to use optical fibers to stimulate nerve cells alone, and use lasers with different wavelengths to open the ion channels of nerve cells, so that nerve cells can be excited accordingly. It is simply to use external optical fibers to stimulate nerve cells and detect their responses. signal stage. Due to the large and uncontrollable optical fiber irradiation area, it is impossible to stimulate each nerve cell in the neural network with multi-point tiny light sources, and it is further impossible to achieve accurate fixed-point culture. Contents of the invention [0003] The purpose of the present invention is to propose a microfluidic light-splitting waveguide structure for light-sensing gen...

AI Technical Summary

Problems solved by technology

Due to the large and uncontrollable optical fiber irradiation area, it is impossible to stimulate each nerve cell in the neural network with multi-point tiny light sources, and it is further impossible to achieve accurate fixed-point culture

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