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Application of traditional Chinese medicine composition in preparation of medicine for treating male infertility

A technology for male infertility and composition, which is applied in the field of traditional Chinese medicine composition, and can solve problems such as reduced sperm count, damaged sperm, and reduced semen density

Active Publication Date: 2014-12-24
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Abnormal semen infertility is a common cause of male infertility. According to research, the causes of abnormal semen include reproductive tract infection, environmental factors, endocrine dysfunction, etc. These factors damage mature sperm and hinder sperm production. Reduce the number of sperm and semen density, etc., and adopt corresponding treatment methods, such as anti-infection, improvement of microcirculation, application of antioxidants, etc., the effect may not be satisfactory

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicine for treating male infertility

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Embodiment 1: the preparation of medicine capsule of the present invention

[0064] prescription:

[0065] Astragalus 70g Talc 14g Prunella vulgaris 21g Ligustrum lucidum 14g

[0066] 21 grams of lychee core, 2.1 grams of amber, 2.8 grams of cinnamon, and 7 grams of cork

[0067] Preparation:

[0068] (1) Weigh the Chinese herbal medicines according to the prescription amount, select them separately, and crush them;

[0069] (2) Take Astragalus membranaceus and Cortex Phellodendri, add 60% ethanol, heat and reflux to extract twice, add 10 times the amount for the first time, extract for 2 hours, add 8 times the amount for the second time, extract for 1 hour, filter the extract, combine, After the ethanol is recovered under reduced pressure, it is concentrated into a clear paste with a relative density of 1.20, dried in vacuum, and the dry paste is used for subsequent use;

[0070] (3) Take Ligustrum lucidum, add 8 times the amount of 80% ethanol, heat and reflux to ...

Embodiment 2

[0076] Embodiment 2: the preparation of pharmaceutical tablet of the present invention

[0077] prescription:

[0078] Astragalus 30 grams, talc 7 grams, Prunella vulgaris 10 grams, Ligustrum lucidum 7 grams

[0079] 10 grams of lychee core, 1 gram of amber, 1.5 grams of cinnamon, 3 grams of cork

[0080] Preparation:

[0081] (1) Weigh the Chinese herbal medicines according to the prescription amount, select them separately, and crush them;

[0082] (2) Take Radix Astragali and Cortex Phellodendri, add 50% ethanol, heat and reflux to extract twice, add 9 times the amount for the first time, extract for 3 hours, add 8 times the amount for the second time, extract for 1.5 hours, filter the extract, combine, After the ethanol is recovered under reduced pressure, it is concentrated into a clear paste with a relative density of 1.25 for subsequent use;

[0083] (3) Take Ligustrum lucidum, add 6 times the amount of 70% ethanol, heat and reflux to extract once, the time is 1 hou...

Embodiment 3

[0088] Embodiment 3: the preparation of medicine capsule of the present invention

[0089] prescription:

[0090] 150 parts of astragalus, 28 parts of talc, 40 parts of Prunella vulgaris, 28 parts of Ligustrum lucidum

[0091] 40 parts of lychee core, 4 parts of amber, 6 parts of cinnamon, and 15 parts of cork.

[0092] (1) Weigh the Chinese herbal medicines according to the prescription amount, select them separately, and crush them;

[0093] (2) Take Radix Astragali and Cortex Phellodendri, add 70% ethanol, heat and reflux to extract twice, add 10 times the amount for the first time, extract for 0.5 hours, add 8 times the amount for the second time, extract for 2 hours, filter the extract, combine, After the ethanol is recovered under reduced pressure, it is concentrated into a clear paste with a relative density of 1.20, dried in vacuum, and the dry paste is used for subsequent use;

[0094] (3) Take Ligustrum lucidum, add 10 times the amount of 90% ethanol, heat and ref...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparation of a medicine for treating male infertility. The traditional Chinese medicine composition is composed of eight traditional Chinese medicines, namely, astragalus membranaceus, talcum, spica prunellae and the like. The traditional Chinese medicine composition has functions of tonifying kidney qi to alleviate water retention and softening hardness to dissipate stagnation, and can be used for effectively treating the male infertility.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in preparing a medicine for treating male infertility. Background technique [0002] In recent decades, with the influence of factors such as environmental pollution, bad living habits and the spread of diseases, human fertility has been declining, and infertility has become a common disease, which is considered by the World Health Organization (WHO) to be related to cardiovascular disease. Along with diseases and tumors, it is one of the three major diseases that endanger human health and life in the 21st century. Male infertility is not an independent disease, but a relatively complex clinical syndrome. Generally, it refers to those who have lived together for more than one year after marriage without taking contraceptive measures, and the woman is infertile due to the man's reasons. ...

Claims

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Application Information

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IPC IPC(8): A61K36/77A61P15/08A61K33/12A61K35/10
Inventor 王永谷春华赵韶华高学东卢会芬
Owner HEBEI YILING MEDICINE INST
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