Application of spanishneedles herb extract in preparation of hypoglycemic agent

Abstract

The invention relates to application of spanishneedles herb extract in preparation of a hypoglycemic agent, effectively solving a problem of hypoglycemic agent preparation. According to the application of the spanishneedles herb extract in preparation of the hypoglycemic agent, the spanishneedles herb extract is obtained by the following steps: taking dried spanishneedles herb, crushing the spanishneedles herb into crude powder, adding the crude powder into alcohol for soaking, refluxing and extracting twice, filtering, combining filtrate, recycling alcohol under reduced pressure until alcohol smell does not exist, concentrating the filtrate into concentrated liquor with relative density of 1.10-1.20 at 50 DEG C, adding distilled water into the concentrated liquor for dispersing the concentrated liquor into a dispersion liquid; placing the dispersion liquid onto a macroporous adsorption resin column, eluting by distilled water, discarding eluant, further eluting by 10% alcohol, discarding the eluant and then eluting with 70% alcohol, collecting the eluant, recycling alcohol under reduced pressure, drying and pulverizing to obtain the spanishneedles herb extract, wherein the content of the general flavones of the spanishneedles herb is over 55%. According to the invention, the raw materials are rich, the preparation method is simple, and the prepared products have hypoglycemic effects and can be used for preparing the hypoglycemic agent, so that the application of the spanishneedles herb extract in preparation of the hypoglycemic agent is realized.

Description

technical field [0001] The invention relates to medicine, in particular to the application of a ghost needle grass extract in the preparation of hypoglycemic drugs. Background technique [0002] The name of ghost needle grass was first seen in "Supplements to Materia Medica", and it is an annual herb of the family Asteraceae. There are ghost hairpin grass ("Materia Medica Supplements"), three-leaf ghost needle, three-leaf ghost needle grass, ghost yellow flower, Shandong old crow grass, mother-in-law needle, ghost bone needle, fork woman, ghost terrestris, sticky grass, steel Forked needles, ghost grass, etc. Ghost needle grass is distributed in tropical and subtropical regions of Asia and America, as well as in East China, Central China, South China, and Southwest China. It grows in roadside wasteland, hillsides, and fields at an altitude of 50-3100 meters. It is a common herbal medicine in China. Gymnosperms. Bitter, flat. Heat-clearing and toxic substances removing, p...

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Problems solved by technology

But so far there is no public report on the application of the extract of ghost needles in the preparation of hypoglycemic drugs

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