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Sub-normal-temperature or low-temperature isolated kidney storage device

A low-temperature preservation, sub-normal temperature technology, applied in the preservation, application, animal husbandry and other directions of human or animal body, can solve problems such as the inability to effectively reflect the activity of organs, avoid the decline of enzyme activity, reduce damage, and slow down the rate of cell metabolism Effect

Inactive Publication Date: 2014-12-10
THE 309TH HOSPITAL OF CHINESE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, when assessing organ viability, hypothermic perfusion can only provide indirect data and cannot effectively reflect the viability of the organ after replantation

Method used

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  • Sub-normal-temperature or low-temperature isolated kidney storage device

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Effect test

Embodiment 1

[0053] During organ preservation, the temperature control device controls the temperature of the organ storage box at a subnormal temperature of 4-32 degrees Celsius. The temperature control device includes a temperature sensor, a cooling device, and a heating device. The temperature sensor, the cooling device, and the heating device are all connected to the controller. One or several temperature sensors are evenly distributed in the organ box or the organ storage room, and the temperature sensor collects data in real time. Save the temperature information of the device, transmit the collected temperature information to the central processor, and the central processor will process the collected temperature signal in real time, obtain the current temperature information of the storage device and display the current temperature information on the man-machine interface, On the other hand, the central processor controls the cooling device or heating device of the temperature contro...

Embodiment 2

[0067] Turn off the temperature control device during organ preservation, and arrange ice cubes around the organ storage box to control the temperature at 0-4 degrees Celsius.

[0068] In the above scheme, the perfusion pipeline includes a sequentially connected peristaltic pump, a filter and a debubbler used as a power device. The peristaltic pump is connected to the liquid storage chamber to provide power for the perfusate in the liquid storage chamber. The motor of the peristaltic pump is connected to the central The processor is connected, and the central processing unit controls the work of the peristaltic pump. A differential pressure sensor is installed at both ends of the filter to monitor the pressure at the filter end. When the filter is clogged and the differential pressure increases, a signal can be transmitted to the controller to activate the alarm device connected to the controller.

[0069] The detection device includes a pressure sensor for monitoring the perf...

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Abstract

The invention relates to a kidney storage device and provides a sub-normal-temperature or low-temperature isolated kidney storage device comprising an organ storage box, a liquid storage chamber, a perfusing pipeline and a controller, wherein the liquid storage chamber is connected with an input opening of the perfusing pipeline through a one-way valve; an output opening of the perfusing pipeline is connected with the organ storage box through a one-way valve; the organ storage box is connected with the input opening of the perfusing pipeline through a one-way valve; the organ storage box is also connected with a urine and perfusate collecting and sampling window; a detecting device connected with the controller is arranged between the perfusing pipeline and the organ storage box; and the organ storage box is provided with a temperature control device. The sub-normal-temperature or low-temperature isolated kidney storage device is used for storing kidneys.

Description

technical field [0001] The present invention relates to an organ preservation device, in particular to a subnormal temperature or low temperature preservation device for isolated kidneys that uses special perfusate to perfuse organs to maintain and / or restore organ viability and activity, and is convenient for storing and / or transporting organs. Background technique [0002] Organ transplantation is the most effective way to treat end-stage organ failure. High-quality donors are the fundamental condition for successful organ transplantation. Therefore, organ preservation, vascular anastomosis and immunosuppressive techniques are called the three cornerstones of organ transplantation. Donor organs will inevitably go through the process of isolated ischemia. The blood type identification and tissue matching of donors, the selection of recipients, the transportation of organs for transplantation, and the implementation of transplantation operations all require a period of waitin...

Claims

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Application Information

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IPC IPC(8): A01N1/02
Inventor 蔡明袁清李州利金海龙詹胜利许亮韦星
Owner THE 309TH HOSPITAL OF CHINESE PEOPLES LIBERATION ARMY
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