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Blood-activating, stasis-resolving and pain-relieving cream and preparation method thereof

A technology for promoting blood circulation and removing blood stasis and cream, applied in the direction of non-central analgesics, ointment delivery, pharmaceutical formulations, etc., can solve the problems of single main function and no good curative effect for waist and leg pain, and achieve uniform and spreadable paste The effect of good resistance and suitable hardness

Active Publication Date: 2014-11-19
汪洁莲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Commonly used ointments include rheumatism plaster, Shangshi Zhipain ointment, etc., but these plasters have better effects for different cases, but they have the disadvantage of single indication function, especially for the treatment of lumbago and leg pain caused by rheumatic hyperplasia. Efficacy

Method used

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  • Blood-activating, stasis-resolving and pain-relieving cream and preparation method thereof
  • Blood-activating, stasis-resolving and pain-relieving cream and preparation method thereof
  • Blood-activating, stasis-resolving and pain-relieving cream and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] 1.1 Preparation of Panax Notoginseng Extract:

[0049] Weigh 200g of Panax notoginseng and extract three times with 75% ethanol under reflux, the first time with 10 times the amount of 75% ethanol for 1.5h, filter, the second time with 8 times the amount of 75% ethanol for 1h, filter, and the third time with 8 Extract with 75% ethanol for 1 hour, filter, combine the three filtrates, and concentrate to 10 times the amount of medicinal materials g / ml to obtain the Panax notoginseng extract.

[0050] 1.2 Preparation of safflower extract:

[0051] Weigh 50g of safflower, extract twice by refluxing, add 10 times the amount of water for the first time, soak in ultrasonic for 0.5h, extract for 1.5h, filter, and add 8 times the amount of water for the second time, extract 1h, filter, and combine the two filtrates. Concentrate to 10 times g / ml of medicinal material to obtain safflower extract.

[0052] 1.3 Preparation of Five Finger Peach Extract:

[0053] Weigh 100g of five-finger hair...

Embodiment 2

[0068] 2.1 Preparation of Panax Notoginseng Extract:

[0069] Weigh an appropriate amount of Panax notoginseng and extract three times with 75% ethanol under reflux, the first time with 15 times the amount of 75% ethanol reflux for 1.5 hours, filter, and the second time with 10 times the amount of 75% ethanol reflux for 1 hour, filter, and the third time Extract with 10 times the amount of 75% ethanol at reflux for 1 hour, filter, combine the three filtrates, and concentrate to 10 times the amount of medicinal materials g / ml to obtain the Panax notoginseng extract.

[0070] 2.2 Preparation of safflower extract:

[0071] Weigh an appropriate amount of safflower, reflux and extract twice, add 18 times the amount of water for the first time, soak in ultrasound for 0.5h, extract for 1.5h, filter, and add 12 times the amount of water for the second time, extract 1h, filter, and combine the two filtrates. Concentrate to 10 times g / ml of medicinal material to obtain safflower extract.

[00...

Embodiment 3

[0088] The physical and chemical indexes of Examples 1 and 2 are as follows:

[0089] 3.1 traits

[0090] The activating blood circulation, removing blood stasis and pain relief cream prepared by the invention is light yellow, suitable in viscosity, suitable in hardness, fine and uniform paste body, good spreadability, cool and comfortable after use, good stability, fresh and elegant smell.

[0091] 3.2 Hot and cold test

[0092] The activating blood circulation, removing blood stasis and pain relieving cream was packaged in a transparent cosmetic bottle and kept in a refrigerator at 4°C for about one week to observe no delamination. In a constant temperature box at 55°C for 24 hours, the paste has no delamination, emulsification, and taste change.

[0093] 3.3 Centrifugal test

[0094] The activating blood circulation, removing blood stasis and pain relief cream was encapsulated in a test tube with a stopper at 3000 r / min and centrifuged for 20 minutes without delamination.

[0095] 3.4...

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Abstract

The invention discloses a blood-activating, stasis-resolving g and pain-relieving cream and a preparation method thereof. The cream includes following substances: safflower seed oil, evening primrose oil, horse oil, hippophae fruit oil, curcuma zedoary oil, mint oil, borneol, menthol, azone, ethanol, a multifunctional emulsifying agent G57, a universal self-emulsifying composite-type emulsifying agent AC-402, a panax notoginseng extract, a safflower extraxt, a radix fici hirtae extract, a cibotium barometz extract, an alangium chinense extract, a zanthoxylum nitidum extraction, 5% sodium carboxymethylcellulose, ethylparaben, 1,2-propanediol, water and essences. Compared with a cream in the prior art, the blood-activating, stasis-dispelling and pain-relieving cream has a cream substrate which contains six traditional Chinese medicine extracts including extracts of panax notoginseng, safflower, radix fici hirtae, cibotium barometz, alangium chinense and zanthoxylum nitidum. The cream has effects of activating blood, resolving stasis, dispersing swelling, relieving pain, clearing heat, cooling blood and promoting tissue regeneration. The cream can enable rheumatism bone pain, bruise, swellings, slight scald, chilblain and the like to be healed early and meanwhile has a basically nourishing function.

Description

Technical field [0001] The invention relates to a cream, in particular to a cream for promoting blood circulation, removing blood stasis and relieving pain, and a preparation method thereof. Background technique [0002] Rheumatic bone pain is a common disease with a high incidence. Generally, two methods of Chinese medicine and Western medicine are used to treat. Western medicine is more effective in treating bone pain caused by inflammation, but for rheumatic bone pain caused by trauma, strain, cold and other factors, Western medicine is generally less effective, even ineffective, and easy to relapse. Western medicine often has Great side effects. [0003] Traditional Chinese medicine for promoting blood circulation, removing blood stasis and relieving pain has a long history, and its clinical application is very extensive. It can not only alleviate and eliminate the suffering of patients, but also eliminate painful diseases to a certain extent. It can improve the rate of cure ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/06A61P29/00
Inventor 孙淑萍李胜利陆晓华钱张超张毓婷
Owner 汪洁莲
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