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Industrial manufacturing method and use of allergen-eliminated partly appropriately-hydrolyzed casein peptide

A moderately hydrolyzed and casein peptide technology, applied in the biological field, can solve the problems of dangerous operation, complex process, difficult industrial production, etc., and achieve the effect of eliminating allergenic activity and easy digestion and absorption

Inactive Publication Date: 2014-08-06
CHINA NAT RES INST OF FOOD & FERMENTATION IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the process uses inorganic acids, the operation is dangerous and the process is complex, and the product may cause amino acid racemization to produce toxic components, which is difficult for industrial production
[0008] In summary, no reports were found on the industrialized manufacturing method of moderately hydrolyzed casein peptides using complex enzymatic hydrolysis combined with ultrafiltration technology

Method used

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  • Industrial manufacturing method and use of allergen-eliminated partly appropriately-hydrolyzed casein peptide

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Embodiment Construction

[0019] The present invention will be described in further detail below in conjunction with specific examples, but the scope of the present invention is not limited. Its specific process route consists of the following steps:

[0020] 1. Preparation of Moderately Hydrolyzed Casein Peptide Powder

[0021] Add 500kg of casein powder into the reaction tank, mix water and casein at a weight ratio of 10%, heat to 85°C, and keep stirring for 20 minutes. Lower the temperature to 50°C, add neutral protease and papain at 3500 units of enzyme per gram of protein, and perform enzymatic hydrolysis for 3.5 hours at a temperature of 50°C. Then, heat the enzymolysis solution to 115°C and inactivate the enzyme for 10 minutes.

[0022] Centrifuge the enzymolysis solution with a tubular centrifuge at a speed of 14000r / min, separate the supernatant and slag, and retain the centrifugation supernatant. The supernatant was filtered with a microfiltration and ultrafiltration device with a pore siz...

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Abstract

The invention discloses an industrial manufacturing method and a use of an allergen-eliminated partly appropriately-hydrolyzed casein peptide, and belongs to the technical field of food nutrition and biotechnology. The industrial manufacturing method utilizes food-grade casein as a raw material and realizes preparation of the appropriately-hydrolyzed casein peptide powder by a composite enzymatic hydrolysis-ultrafiltration combined technology. The allergen-eliminated partly appropriately-hydrolyzed casein peptide has average molecular weight of 1500Da-3000Da, protein antigenicity reduced by more than 85%, and has main allergen alpha s1-casein content reduced by more than 95% than casein content. Compared with other appropriately-hydrolyzed casein products on the market, the allergen-eliminated partly appropriately-hydrolyzed casein peptide has obviously reduced sensitization activity and has a small bitter taste and good processing performances. The allergen-eliminated partly appropriately-hydrolyzed casein peptide prepared by the industrial manufacturing method can be used as a novel functional nutrient in common foods, sports functional foods, infant formula milk powder and foods, adult milk powder and foods, milk powder and foods for middle and old age, health foods and medicines and has a wide market prospect.

Description

technical field [0001] The invention relates to an industrialized production method for preparing moderate hydrolyzate of hypoallergenic casein by using casein as raw material. The product can be applied to common food, adult milk powder and food, middle-aged and elderly milk powder and food, infant formula milk powder and food, sports Functional food, health food and medicine belong to the field of biotechnology. Background technique [0002] Cow's milk is the most important source of milk protein in the world. Because of its high nutritional value, cow's milk has become one of the most consumed protein resources for human beings. Its main nutritional function is reflected in infant formula food such as breast milk substitute food or the elderly and patients. nutritious food. At the same time, milk allergy is also the most common food allergy in infants and young children, present in about 2%-3% of infants and young children, and can cause eczema, itching, rash, urticaria,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P21/06A23L1/305A23C9/152A61K38/01
Inventor 蔡木易谷瑞增林峰易维学鲁军马勇董哲潘兴昌马永庆徐亚光金振涛陈亮刘文颖刘艳马涛
Owner CHINA NAT RES INST OF FOOD & FERMENTATION IND CO LTD
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