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Traditional Chinese medicine composition for treating non-alcoholic fatty liver and preparation method thereof

A non-alcoholic, fatty liver technology, applied in the field of traditional Chinese medicine composition and its preparation for the treatment of non-alcoholic fatty liver, to achieve good clinical effect

Inactive Publication Date: 2014-07-30
南京欣昊医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no drug with significant curative effect in western medicine for the treatment of fatty liver, and the drugs that regulate blood lipid are mainly used as adjuvant treatment for fatty liver

Method used

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  • Traditional Chinese medicine composition for treating non-alcoholic fatty liver and preparation method thereof
  • Traditional Chinese medicine composition for treating non-alcoholic fatty liver and preparation method thereof
  • Traditional Chinese medicine composition for treating non-alcoholic fatty liver and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] A traditional Chinese medicine combination medicine for treating non-alcoholic fatty liver, comprising the following components in parts by weight:

[0065] 600 parts of Scutellaria baicalensis and 500 parts of Coptis chinensis.

[0066] Preparation methods include:

[0067] Extract Scutellaria baicalensis and Coptis chinensis with 50% for 3 times, each time for 1.5 hours, combine the filtrates, recover ethanol under reduced pressure until there is no alcohol smell, dry under reduced pressure and pulverize into fine powder, add appropriate amount of starch, dextrin, magnesium stearate, 50 % ethanol to granulate, dry, and film-coat.

Embodiment 2

[0069] A traditional Chinese medicine combination medicine for treating non-alcoholic fatty liver, comprising the following components in parts by weight:

[0070] 500 parts of Scutellaria baicalensis and 500 parts of Coptis chinensis.

[0071] Preparation methods include:

[0072] Scutellaria baicalensis and Coptis chinensis were extracted 3 times with 60%, the first time was 1 hour, the second time was 1 hour, and the third time was 0.5 hours, the filtrate was combined, the ethanol was recovered under reduced pressure until there was no alcohol smell, dried under reduced pressure and crushed into fine powder, added Appropriate amount of starch, dextrin, magnesium stearate and 50% ethanol are granulated, dried, and film-coated.

Embodiment 3

[0074] A traditional Chinese medicine combination medicine for treating non-alcoholic fatty liver, comprising the following components in parts by weight:

[0075] 400 parts of Scutellaria baicalensis and 600 parts of Coptis chinensis.

[0076] Preparation methods include:

[0077] Extract Scutellaria baicalensis and Coptis chinensis with 70% twice, each time for 1 hour, combine the filtrates, recover ethanol under reduced pressure until there is no alcohol smell, dry under reduced pressure and pulverize into fine powder, add appropriate amount of starch, dextrin, magnesium stearate, 50 % ethanol to granulate, dry, and film-coat.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating non-alcoholic fatty liver and a preparation method thereof. The composition is prepared from the following medicinal plants or decoction pieces through extracting: 100-600 parts of scutellaria baicalensis and 100-600 parts of coptis chinensis. The composition disclosed by the invention has effects of inducing dieresis and dispersing blood stasis, clearing away heat and toxic materials, protecting the liver and descending the turbid, is widely used for fatty liver, chronic hepatitis and hepatic fibrosis caused by various causes, and has a better curative effect for various fatty livers caused by obesity, diabetes, hypertension, hepatitis, and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating non-alcoholic fatty liver made from decoction pieces of traditional Chinese medicines and a preparation method thereof. Background technique [0002] Non-alcoholic fatty liver (NAFL) is a metabolic stress-induced liver injury closely related to insulin resistance and genetic susceptibility. Its pathological changes are similar to those of alcoholic liver disease, but the patient has no history of excessive drinking. Alcoholic simple fatty liver, nonalcoholic steatohepatitis and its associated cirrhosis and hepatocellular carcinoma. Epidemiology shows that the disease affects 10-24% of the world's population on average, and the prevalence among obese people is as high as 57-74%, significantly exceeding the prevalence of hepatitis B, hepatitis C and alcoholic liver disease. become the most common liver disease. ...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61P1/16
Inventor 王宁白凤阁
Owner 南京欣昊医药科技有限公司
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