A metal vascular clip capable of directional degradation and absorption and its preparation method

A blood vessel clip and metal technology, applied in wound clips, medical science, surgery, etc., can solve the problems of clip body fracture failure, cusp potential corrosion, uncontrollable degradation, etc., and achieve satisfactory closed clip sealing effect and good biocompatibility Good performance and good sealing effect

Active Publication Date: 2016-02-24
SUZHOU ORIGIN MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are still many deficiencies in the technical solution provided by this patent. First, the technical solution mentioned in this patent fails to effectively solve the degradation problem of magnesium metal, and the serious pitting phenomenon when magnesium metal is degraded is a common problem in this field. Commonly known technical difficulties, if this problem is not solved properly, it will lead to uncontrollable degradation and greatly increase the risk of using the device; secondly, the structure of the vascular clip described in the technical solution mentioned in the patent is similar to the traditional titanium clip, but The tensile strength and plasticity of magnesium metal materials are far lower than those of titanium materials. Adopting such a structure will cause the sealability after closure to fail to meet actual needs; the clip body will fracture and fail when it deforms plastically at a large angle; the inner wall of the blood vessel clip There is a through groove on the top, which will lead to severe cusp potential corrosion, which will accelerate the degradation rate here, and the clip body will break and fail in a short time. Therefore, the technical solution mentioned in this patent cannot fully meet the actual situation of magnesium metal vascular clips. need

Method used

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  • A metal vascular clip capable of directional degradation and absorption and its preparation method
  • A metal vascular clip capable of directional degradation and absorption and its preparation method
  • A metal vascular clip capable of directional degradation and absorption and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The magnesium alloy ingot with a magnesium content of more than 98% is extruded into a 3 mm thick magnesium alloy plate, the extrusion ratio is 25, the extrusion temperature is 300 ° C, and the grain diameter of the formed plate is ≤ 20 μm. The formed plate is cold-rolled, and the single deformation of cold rolling is 3%. When the cumulative deformation is 25%, annealing is performed at a temperature of 300°C for 200 seconds, and then the above cold-rolling process is repeated until the thickness of the plate is 0.8mm, its grain diameter ≤ 10μm, tensile strength > 180MPa, elongation > 5%.

[0051] The plate obtained by the above processing steps is processed by wire cutting to obtain a blood vessel clip, and the structure is as follows figure 1 Middle blood vessel clamp upper arm 2, blood vessel clamp lower arm 3, tail O-shaped structure 4, upper arm fixing hook 5, lower arm fixing hook 6, lower arm elastic structure 7, inner sealing surface of blood vessel clamp 8, ass...

Embodiment 2

[0062] More than 99.99% of magnesium ingots are extruded into 3mm thick magnesium plates, the extrusion ratio is 25, the extrusion temperature is 300°C, and the grain diameter of the formed plates is ≤20μm, and the extruded plates are cooled Rolling, the single deformation of cold rolling is 3%, when the cumulative deformation is 25%, annealing is carried out at a temperature of 300°C and a time of 200 seconds, and then the above cold rolling process is repeated until the plate thickness is 0.8mm. Grain diameter ≤ 10μm, tensile strength > 180MPa, elongation > 5%.

[0063] The plate obtained by the above processing steps is processed by wire cutting to obtain a blood vessel clip, and the structure is as follows figure 1 Middle 2 vascular clip upper arm, 3 vascular clip lower arm, 4 tail O-shaped structure, 5 upper arm fixed hook, 6 lower arm fixed hook, 7 lower arm elastic structure, 8 inner sealing surface of vascular clip, 9 assembly upper fixed structure, 10 assembly Lower ...

Embodiment 3

[0067] More than 99.99% of magnesium ingots are extruded into 3mm thick magnesium plates, the extrusion ratio is 35, the extrusion temperature is 200°C, the grain diameter of the formed plates is ≤12μm, and the extruded plates are cooled Rolling, the single deformation of cold rolling is 5%, when the cumulative deformation is 40%, annealing is carried out at a temperature of 250 ° C for 60 seconds, and then the above cold rolling process is repeated until the thickness of the plate is 0.8mm. Grain diameter ≤ 4μm, tensile strength > 210MPa, elongation > 7%.

[0068] The plate obtained by the above processing steps is processed by wire cutting to obtain a blood vessel clip, and the structure is as follows figure 1 Middle 2 vascular clip upper arm, 3 vascular clip lower arm, 4 tail O-shaped structure, 5 upper arm fixed hook, 6 lower arm fixed hook, 7 lower arm elastic structure, 8 inner sealing surface of vascular clip, 9 assembly upper fixed structure, 10 assembly Lower fixed s...

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Abstract

A metal vascular clamp capable of being directionally degraded and absorbed and a manufacturing method therefor. The vascular clamp comprises an upper arm (2), a lower arm (3) and a tail O-shaped structure (4) all used for closing a blood vessel (1). A V-shaped structure is formed by the upper arm (2), the lower arm (3) and the tail O-shaped structure (4) before closing. The end of the upper arm (2) and the end of the lower arm (3) are provided with self-locking structures (5, 6) matched with each other. When the metal vascular clamp is used, the blood vessel needing to be closed is placed in a gap between the upper arm (2) and the lower arm (3) of the V-shaped structure, and the upper arm (2) and the lower arm (3) are squeezed to enable the included angle therebetween to be gradually decreased until the self-locking structures (5, 6) of the upper arm and the lower arm are mutually locked and closed. The outer side and the inner side of the upper arm (2) and the outer side and the inner side of the lower arm (3) are provide with different microstructures and electric potential differences, the grains on the outer sides are dimensionally larger than the grains on the inner sides and the electric potential differences on the outer sides are lower than the electric potential differences on the inner sides, so that directional degradation from the outer side to the inner side is achieved after the vascular clamp is closed. Through the change of the tissue structure differences of different parts of the material of the vascular clamp in a directional way, the electric potential differences thereof can be changed, and thus the directional degradation in different orders of degradation is achieved.

Description

technical field [0001] The invention relates to the field of implantable medical device products, in particular to a metal blood vessel clip used for permanently closing blood vessels in a human body during surgery and a preparation method thereof. Background technique [0002] Clinically, when doctors perform abdominal and thoracic surgical resections, they will ligate and close the active bleeding blood vessels near the surgical site that cannot be sutured or are unnecessary to suture, so as to avoid bleeding during and after surgery. Existing closure techniques include two types. First, suture the required ligation and closure sites with thread, which takes a long time to operate and is difficult to operate. It requires high suturing skills for doctors and is time-consuming and laborious. The long-term operation also has a great impact on the patient. Injury, and it is almost impossible to operate under the speculum; Second, use metal titanium vascular clips to clamp and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/122C22F1/06B23P15/00A61L31/02A61L31/14
CPCA61B17/1227A61B2017/00004A61B2017/00526
Inventor 刘静怡张绍翔张元壮姜曼徐海东赵常利张小农
Owner SUZHOU ORIGIN MEDICAL TECH
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