Brain nuclei Granger causal analysis method based on RYGB surgery weight losing

Abstract

The invention discloses a brain nuclei Granger causal analysis method based on RYGB surgery weight losing. The method comprises the following steps of obtaining functional magnetic resonance data in a resting state scanning mode, preprocessing the data, carrying out regional homogeneity analysis on the preprocessed data, defining regions of interest according to the difference area of the brain of an obese patient one month before and after surgery, carrying out Granger causal analysis, selecting two areas from selected regions of interest at random, extracting time sequences of the two areas, calculating a Granger causal value between the two areas by adopting a first-order autoregressive model, and carrying out normalization, wherein the step of preprocessing the data comprises the steps of time rectification, head moving rectification and space standardization. According to brain nuclei Granger causal analysis method based on the RYGB surgery weight losing, the RYGB surgery weight losing changes the functions of brain reward loops, brain cognitive loops and brain drive loops and the mutual cause and effect relation among the loops, the crapulent degree of the obesity patient is relieved, and iconography proofs are provided for development of central nervous system medicine.

Description

technical field [0001] The invention belongs to the technical field of medical image processing and analysis, in particular to a method for Granger causality analysis of brain nuclei based on RYGB surgery for weight loss. It can be used to describe the mutual causal relationship between nuclei, thus providing imaging evidence for the development of central drug. Background technique [0002] At present, all countries in the world are facing the global problem of obesity. It is defined as a disease by the World Health Organization (WHO). It is the third most threatening factor to human health after cardiovascular disease and cancer. The number of obese people in the world has exceeded 400 million (about 6% of the total population) and about 1.6 billion overweight people (about 24% of the total population), WHO predicts that by 2015 there will be 2.3 billion overweight adults and 700 million obese people, and by the end of 2008, China The number of obese people has exceeded 9...

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Problems solved by technology

[0006] The purpose of the embodiments of the present invention is to provide a method for Granger causality analysis of brain nuclei based on RYGB surgery weight loss, aiming to solve the existing lack of finding the function of brain nuclei in the resting state from the perspective of the mutual causal relationship between nuclei in the circuit problems with differences

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