Oral matrix film and preparation method thereof
一种基质膜、口腔的技术,应用在口腔基质膜及其制备领域,能够解决不能确保植骨治疗获得成功、缺乏可生物降解等问题,达到设备成本低廉、组织附着性好、促进细胞繁殖的效果
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Embodiment 1
[0022] The base material of the oral matrix film in this example is made of polylactic acid polymer (PDLLA), acetyl tributyl citrate (ATBC) and L-polylactic acid (PLLA), in which polylactic acid polymer is 77%, acetyl citric acid 13% for tributyl ester and 10% for L-polylactic acid.
[0023] The molecular weight of polylactic acid polymer is 200,000, and the molecular weight of L-polylactic acid is 50,000 to 80,000. The molecular weight of PDLLA is about 200,000, which is conducive to processing and molding. The function of adding PLLA is to enhance the physical strength of the film. The degradation time of PLLA is slower than that of PDLLA, so its molecular weight is lower, which is helpful for degradation. The intrinsic viscosity of the final oral matrix film substrate is >1.0 dl / g.
[0024] The oral matrix membrane has a three-layer structure, namely an upper layer 1 , a middle layer 2 and a bottom layer 3 , and each layer is provided with a through hole 4 .
[0025] The ...
Embodiment 2
[0028] The oral matrix film of this example is the same as Example 1 except that the proportion of the base material components is 89.5% of polylactic acid polymer, 10.5% of acetyl tributyl citrate, and 0 of L-polylactic acid.
Embodiment 3
[0030] The oral matrix film of this example is the same as Example 1 except that the proportion of the base material is 75% of polylactic acid polymer, 13% of acetyl tributyl citrate, and 12% of L-polylactic acid.
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