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Formula of Equine trypanosomiasis evansi treatment drug

An espondylosis and animal technology, which is applied in the field of drug formulations for treating equine spondylosis, can solve problems such as drug resistance of parasites, and achieves no residues of drugs, wide sources and reasonable formulations Effect

Inactive Publication Date: 2014-04-30
QINGDAO DERUI JUNFA BIOLOGY TECH +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, long-term use of western medicine will cause the parasites to develop drug resistance, and traditional Chinese medicine for the treatment of equine trypanosomiasis has not yet been developed.

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0035] The present invention also provides a preparation method of any one of the above-mentioned pharmaceutical prescriptions for treating equine spineworm disease. The preparation method of the traditional Chinese medicine composition includes the following steps:

[0036] In the first step, the components are mixed in proportion and crushed into powder;

[0037] In the second step, add the powder obtained in the first step to cold water and soak for 6-12 hours, decoc on a slow fire for 3 to 5 hours, filter the decoction to obtain the first filtrate. The added water The quality of the powder is 2 to 4 times that of the powder obtained in the first step;

[0038] In the third step, the filter residue obtained in the second step is added to cold water again, decocted on a slow fire for 2 to 4 hours, and the second filtrate is obtained by filtration. The quality of the added water is 2 to the mass of the powder obtained in the second step. 4 times;

[0039] In the fourth step, the fir...

Embodiment 1

[0058] Chuan Neem Seed 25g, Bupleurum 20g, Lychee Seed 20g, Fennel 20g, Frankincense 10g, Qianghuo 10g and Duhuo 25g. Mix and pulverize into powder with a particle size of 200 mesh; add 100ml of rice wine to the powder and mix evenly. When using, administer.

Embodiment 2

[0060] Chuan Neem Seed 24g, Bupleurum 19g, Lychee Seed 19g, Fennel 20g, Frankincense 9g, Qianghuo 9g, Solanum Leaf 24g and Evodia Evodia 18g. Mix and pulverize into powder with a particle size of 180 mesh; add 90ml of rice wine to the powder and mix evenly. When using, administer.

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PUM

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Abstract

The present invention provides a formula of an Equine trypanosomiasis evansi treatment drug. The drug comprises the following raw material herbs: melia toosendan, bupleurum chinense, lychee seed, fennel, frankincense, notopterygium incisum and heracleum hemsleyanum. According to the present invention, spleen-stomach warming, coldness expelling, qi benefiting and splenic yang invigorating are adopted as the treatment principle, the formula is reasonable, the preparation process is simple, and the application range is wide; and the drug is prepared from the pure Chinese herbs, and has characteristics of wide source, low cost, high cure rate, no drug residue and no toxic-side effect, especially the plant cell wall is damaged at a maximum after ultrafine crushing, the defects of high crude fiber content and difficult effective component dissolution of the traditional drug powder are solved, and the drug is easily absorbed by horses, has effects of significant relieving, pain relieving, body function regulating and effective foal scrotum hernia treatment, and further provides characteristics of convalescent period shortening and no recurrence compared with the western medicine treatment.

Description

Technical field [0001] The invention relates to the technical field of pharmaceutical engineering, in particular to a pharmaceutical formula for the treatment of equine spineworm disease. Background technique [0002] Trypanosomiasis evansi (also known as "Saura disease") is a blood protozoal disease caused by Trypanosoma evansi, which occurs mostly in tropical and subtropical regions. The clinical features are progressive weight loss, anemia, jaundice, high fever, myocardial failure, often accompanied by surface edema and neurological symptoms. [0003] Clinical symptoms: Acute cases are mostly atypical missed fever (mostly above 40 ℃) or flaccid fever. During fever, shortness of breath, increased pulse rate, blood picture, urine, spirit, appetite, physical fitness, etc. have obvious new changes. In general, trypanosomes can be detected in the blood during the initial stage of fever. The detection rate of trypanosomes in the blood in acute cases is more consistent with the incre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/77A61P7/00A61P33/02
Inventor 邢金凤张志鹏李成修
Owner QINGDAO DERUI JUNFA BIOLOGY TECH
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