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A kind of Shuxin Jiangzhi Tablet and its preparation method

A lipid-lowering and relaxing technology, which can be used in pharmaceutical formulations, cardiovascular system diseases, medical preparations with inactive ingredients, etc.

Active Publication Date: 2017-01-04
YUNNAN PHYTOPHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to improve the stability of Shuxin Jiangzhi Tablets, solve the quality problems of Shuxin Jiangzhi Tablets that are easy to absorb moisture and crack easily during storage, and provide a kind of Shuxin Jiangzhi Tablets and its preparation method

Method used

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  • A kind of Shuxin Jiangzhi Tablet and its preparation method
  • A kind of Shuxin Jiangzhi Tablet and its preparation method
  • A kind of Shuxin Jiangzhi Tablet and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The drug formulation consists of:

[0045] The mass percentages of raw and auxiliary materials are: Shuxin Jiangzhi Tablet Dry Cream 75%, Buckwheat Pollen 7%, Microcrystalline Cellulose 10%, Calcium Sulfate 2%, Aroma Essential Oil 1%, Sodium Carboxymethyl Starch 4.5%, Silicon Dioxide 0.3% , Magnesium stearate 0.2%.

[0046] Preparation:

[0047] (1) Weigh Shuxin Jiangzhi Tablets Dry Cream, Buckwheat Pollen, Microcrystalline Cellulose, Calcium Sulfate, Carboxymethyl Starch Sodium and Lubricant according to the formula and pass through a 60-mesh sieve respectively;

[0048] (2) Add purified water to ethanol to prepare a wetting agent with a concentration of 75% by mass;

[0049] (3) Mix Shuxinjiangzhi Tablets dry paste, buckwheat pollen, microcrystalline cellulose, and calcium sulfate evenly;

[0050] (4) Add the previously prepared wetting agent, make soft materials, and granulate with a 10-mesh sieve;

[0051] (5) The wet granules are dried at 70°C, sieved with a 10...

Embodiment 2

[0053] The drug formulation consists of:

[0054] The mass percentage of raw and auxiliary materials is: 51% of Shuxin Jiangzhi Tablet dry cream, 10% of rapeseed pollen, 18.5% of microcrystalline cellulose, 5.7% of calcium sulfate, 2.5% of balsamic essential oil, 11% of sodium carboxymethyl starch, 0.5% of talc, Magnesium Stearate 0.8%.

[0055] Preparation:

[0056] (1) Weigh Shuxin Jiangzhi Tablet Dry Cream, Rapeseed Pollen, Microcrystalline Cellulose, Calcium Sulfate, Carboxymethyl Starch Sodium and Lubricant according to the formula and pass through 80-mesh sieve respectively;

[0057] (2) Add purified water to ethanol to prepare a wetting agent with a concentration of 85% by mass;

[0058] (3) Mix Shuxinjiangzhi Tablets dry ointment, rapeseed pollen, microcrystalline cellulose, and calcium sulfate evenly;

[0059] (4) Add the previously formulated wetting agent to make soft materials and granulate with a 16-mesh sieve;

[0060] (5) The wet granules are dried at 75°C, si...

Embodiment 3

[0062] The drug formulation consists of:

[0063] The mass percentages of raw and auxiliary materials are: Shuxin Jiangzhi Tablet Dry Cream 20%, Buckwheat Pollen 8%, Rapeseed Pollen 7%, Microcrystalline Cellulose 30%, Calcium Sulfate 7%, Dalbergia Essential Oil 5%, Carboxymethyl Starch Sodium 20%, Talc powder 1%, magnesium stearate 2%.

[0064] Preparation:

[0065] (1) Weigh Shuxin Jiangzhi Tablet Dry Cream, Buckwheat Pollen, Rapeseed Pollen, Microcrystalline Cellulose, Calcium Sulfate, Carboxymethyl Starch Sodium and Lubricant according to the formula and pass through a 100-mesh sieve;

[0066] (2) Add purified water to ethanol to prepare a wetting agent with a concentration of 90% by mass;

[0067] (3) Mix Shuxinjiangzhi Tablets dry paste, buckwheat pollen, microcrystalline cellulose, and calcium sulfate evenly;

[0068] (4) Add the previously prepared wetting agent, make soft materials, and granulate with a 20-mesh sieve;

[0069] (5) Dry the wet granules at 80°C, siev...

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Abstract

The invention provides a heart nourishing and lipid lowering tablet and a preparation method thereof. Through changing accessory formula in an original production process, stability of the heart nourishing and lipid lowering tablet is effectively improved, and quality problems of the heart nourishing and lipid lowering tablet which is easy to absorb moisture and easy to get cracked are solved. Raw material and accessory formula of the production process consists of 20-75% of a dry paste of heart nourishing and lipid lowering tablet, 7-15% of pollen, 10-30% of microcrystalline cellulose, 2-7% of calcium sulfate, 1-5% of dalbergia wood volatile oil, 4.5-20% of carboxymethyl starch sodium and the balance of a lubricating agent. The heart nourishing and lipid lowering tablet prepared by the invention is smooth in surface, stable in performance and suitable for mass production; product quality meets national drug standard requirements.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to a Shuxin Jiangzhi tablet and a preparation method thereof. Background technique [0002] Shuxin Jiangzhi Tablets are prepared from 11 medicinal materials such as purple salvia miltiorrhiza and pollen. The role of lipid-lowering and prevention of atherosclerosis. [0003] Changes in social life style and rhythm have led to a substantial increase in the number of people suffering from high blood pressure, arteriosclerosis, obesity, coronary heart disease, angina pectoris and myocardial infarction. Hyperlipidemia is a key factor for various cardiovascular and cerebrovascular diseases. Shuxin Jiangzhi Tablets has good curative effect, few side effects, and definite clinical curative effect. It has won the trust of consumers and is widely used. [0004] During the storage process, it was found that Shuxin Jiangzhi Tablets on the market and originally produced by our com...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/8962A61K47/38A61K47/04A61P3/06A61P9/10
Inventor 李云仙叶亚斌段昆花李俊
Owner YUNNAN PHYTOPHARML
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