Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of arctigenin in preparation of anti-infectious immunity drugs

A technology of arctigenin and medicine, which is applied in the field of medicine, can solve the problems such as the application of arctigenin anti-infective immune drugs that have not been reported, and achieve the effects of improving immunity of the body, low toxic and side effects, and price advantage.

Inactive Publication Date: 2014-03-12
LUNAN PHARMA GROUP CORPORATION
View PDF0 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It has been proved that arctigenin has stronger biological activity than arctiin, such as significant antibacterial, antiviral, antitumor, anti-PAF receptor and calcium antagonistic activities, but arctigenin has not been reported in the prior art Application in preparation of anti-infection immunomedicine

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of arctigenin in preparation of anti-infectious immunity drugs
  • Application of arctigenin in preparation of anti-infectious immunity drugs
  • Application of arctigenin in preparation of anti-infectious immunity drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 arctigenin injection

[0025] Prescription:

[0026] Arctigenin 10g

[0027] PEG-400 2L

[0028] Add 0.9% sodium chloride solution to 10L

[0029] Preparation Process:

[0030] Add the prescribed amount of PEG-400 to arctigenin, stir to dissolve, add the prescribed amount of 0.9% sodium chloride solution, stir evenly, adjust the pH to 3 with citric acid, add 0.5% activated carbon for needles, stir, and decarbonize, that is have to.

Embodiment 2

[0031] Embodiment 2 arctigenin injection

[0032] Prescription:

[0033] Arctigenin 10g

[0034] PEG-400 3L

[0035] Add 0.9% sodium chloride solution to 10L

[0036] Preparation Process:

[0037] Add the prescribed amount of PEG-400 to arctigenin, stir to dissolve, add 0.9% sodium chloride solution to 10L, stir evenly, adjust the pH to 4 with citric acid, add 0.5% activated carbon for needles, stir, and decarbonize to obtain .

Embodiment 3

[0038] Embodiment 3 arctigenin injection

[0039] Prescription:

[0040] Arctigenin 10g

[0041] PEG-400 1L

[0042] Add water for injection to 10L

[0043] Preparation Process:

[0044] Add the prescribed amount of PEG-400 to arctigenin, stir to dissolve, add water for injection to 10L, stir evenly, adjust the pH to 6.5 with citric acid, add 0.5% activated carbon for needles, stir, decarbonize, and the product is ready.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides application of arctigenin in preparation of anti-infectious immunity drugs, which belongs to the field of medicine. Arctigenin is a natural monomer extracted from the traditional Chinese medicine burdock; it is discovered that arctigenin can substantially improve the clearance index and the phagocytic index of an immunocompromised patient and enhance non-specific immunity of the patient, exerts good treatment effects on infection caused by parasites, bacteria and viruses and especially has an excellent treatment effect on infectious diseases caused by Gram-positive bacteria. Arctigenin has the advantages of definite therapeutic effects, small toxic and side effects and wide medical application prospects when used for treatment of infectious diseases.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of arctigenin in the preparation of anti-infection and immune drugs. Background technique [0002] Infectious diseases are a general term for diseases caused by pathogenic microorganisms, which mainly include bacterial infections, viral infections, fungal infections, parasitic infections, etc., among which bacterial infections and viral infections are the most common. Infectious diseases are very common in clinical practice, and it is also a problem that doctors often face. For example, the patient is infected with other diseases due to poor physical fitness and resistance to germs during the treatment period. People who have just had surgery, if they don't pay attention to disinfection and protection of the incision, they are easy to be infected and not easy to heal. There are also patients who have pneumonia during the healing period due to major surgery. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/365A61P37/04A61P31/00
Inventor 赵志全陈凯王洪臣
Owner LUNAN PHARMA GROUP CORPORATION
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com