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Method for evaluation of high insulin type obesity gene physique

An obesity gene and high insulin technology, applied in the field of molecular biology, can solve problems such as reduced fatty acid oxidation, obesity, and decreased insulin sensitivity

Inactive Publication Date: 2014-02-26
上海中优医药高科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Mutation or abnormal expression of ADIPOQ can cause low plasma adiponectin concentration, which can easily lead to decreased insulin sensitivity and fatty acid oxidation, leading to obesity

Method used

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  • Method for evaluation of high insulin type obesity gene physique
  • Method for evaluation of high insulin type obesity gene physique
  • Method for evaluation of high insulin type obesity gene physique

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Experimental program
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Embodiment Construction

[0121] The purpose of the present invention is to provide a method for evaluating the genetic constitution of hyperinsulinemic obesity, which can allow the examinee to understand his own genetic constitution and the cause of personal obesity potential before considering diet and exercise, so as to choose the most suitable The individualized nutrition and exercise slimming method breaks down the expression patterns of various obesity genes one by one to achieve the most effective and healthy weight loss effect.

[0122] In order to achieve the above objectives, the present invention provides a method for assessing the genetic constitution of hyperinsulinemic obesity. The specific steps are:

[0123] Step 1: Types of samples tested and sampling methods

[0124] Use a sampling swab to swab the left and right cheeks in the mouth at least 40 times up and down to ensure that sufficient cell samples are collected;

[0125] Step 2: Extraction method of genomic DNA

[0126] The geno...

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Abstract

The invention discloses a method for evaluation of high insulin type obesity gene physique. The method is characterized by simultaneously detecting and analyzing the SNPs site genotype of individual LEP gene, LEPR gene, IL-6 gene, and ADIPOQ gene to provide high insulin type obesity physique evaluation for all detection subjects. According to the method, the detection subjects can firstly get acquaintance with the gene physique condition of themselves and personal obesity potential cause before considering weight reducing by diet and exercises, so that a most suitable individualized nutrition and exercise weight-loss way can be selected to destroy various obesity gene expression patterns, thus achieving a most effective and healthy weight loss effect.

Description

technical field [0001] The invention relates to a method for evaluating the genetic constitution of hyperinsulinemic obesity, which can be used for evaluating the genetic constitution of hyperinsulinemic obesity, and specifically prompts subjects to choose different weight loss strategies according to their genetic constitution, belonging to the technical field of molecular biology. Background technique [0002] Obesity is a calorie metabolism disorder, where the intake of calories exceeds the calories consumed, resulting in excessive accumulation of body fat. It is generally considered to be obese if it exceeds 20% of the standard weight measured by height. Obesity is a chronic disease closely related to genetic factors and lifestyle. It can cause elevated blood lipids, which can easily lead to fatty liver, arterial vascular disease, heart disease, and diabetes. Obese children can also cause sexual dysfunction and lead to The morbidity and mortality of various diseases inc...

Claims

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Application Information

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IPC IPC(8): C12Q1/68
CPCC12Q1/6888C12Q2600/156
Inventor 傅咏南王校毛丹丹张奕卞雪莲潘峰乐涵骏
Owner 上海中优医药高科技股份有限公司
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