Quick multi-index detection method for Paris polyphylla medicinal materials

Abstract

The invention provides a quick multi-index detection method for Paris polyphylla medicinal materials. The method comprises the following steps: collecting different batches of Paris polyphylla medicinal materials as samples; determining the content of various saponin monomers and total saponin in the samples through using a liquid chromatography method; determining the content of moisture in the samples through using a drying and weighing method; collecting near-infrared spectrum data of the samples; establishing a model by selecting an appropriate modeling wave band and a spectrum preprocessing method, quickly analyzing and quantifying various saponin monomers, the total saponin and the moisture through using a partial least squares regression method; quickly determining the content of various saponin monomers, the total saponin and the moisture in unknown samples through using the established model; judging whether the Paris polyphylla medicinal materials can be put into subsequent production links such as extraction according to the content of the total saponin and the content of the moisture, which are measured through using a near infrared spectroscopy technology. By applying a near-infrared analysis technology to determination of the content of saponin components and the moisture in the Paris polyphylla medicinal materials, compared with a conventional analysis method, the quick multi-index detection method for the Paris polyphylla medicinal materials is quick and efficient, and has an application prospect of field medicinal material screening and comprehensive quality evaluation.

Description

technical field [0001] The invention belongs to the field of near-infrared detection, and in particular relates to a multi-indicator rapid detection method for the medicinal material of Pachyphylla sinensis. Background technique [0002] The traditional Chinese medicine Zhonglou Paris polyphylla Smith Var. yunnanensis (Franch.) Hand.-Mazz. or Aesculus Prais polyphylla Smith Var.chinensis (Franch.) The dry rhizome of Hara, its main chemical composition is steroidal saponin, and contains β-ecdysone, polysaccharide, flavonoid glycoside and amino acid, which has strong physiological and pharmacological activities, including anti-tumor, hemostasis and pain relief, antibacterial Anti-inflammatory, immune regulation and other effects, widely used in clinical practice. [0003] Raw material inspection is the source of process quality analysis and control. Due to differences in geographical location, climatic conditions, growth environment and other factors, the content and ...

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Problems solved by technology

[0005] "Quality Evaluation of Chonglou Commodity Medicinal Materials in Sichuan-Yunnan Region" (Yin Hongxiang et al., "Chinese Medicinal Materials", July 2007, Volume 30, No. 7, p771-774), although the conditions of high performance liquid chromatography are disclosed, but its parameters The parameters in this patent are quite different

In addition, there are no domestic and foreign reports on the application of near-infrared analysis technology in the content determination of key quality control indicators in Chonglou medicinal materials. Therefore, it is very necessary to develop a method to quickly detect the key quality control indicators in Chonglou medicinal materials. It helps to improve the stability, safety and effectiveness of traditional Chinese medicine products

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