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Premenstrual ease pharmaceutical composition and preparation technique thereof

A composition and medicine technology, applied in the field of premenstrual drug composition and preparation technology thereof, can solve the problems of slow recuperation, injury to the body, insignificant curative effect and the like

Inactive Publication Date: 2013-12-18
XIANGYU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The current Western medicine treatment has a long cycle, high treatment cost, and damage to the body, easy to relapse, and the curative effect is not obvious
At present, traditional Chinese medicine treatment is a relatively common way. Traditional Chinese medicine mainly focuses on conditioning, but it all depends on gradual recuperation, and most of the current prescriptions are for different people. The treatment cycle is long, easy to relapse, and the curative effect is not obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A premenstrual medicinal composition using Chinese herbal medicines as raw materials, which is prepared from raw materials with the following weight ratios:

[0023] 30 parts of Bupleurum, 26 parts of Platycodon, 23 parts of Longan, 20 parts of Motherwort, 20 parts of Salvia,

[0024] 18 parts of seaweed, 18 parts of Fangfeng, 16 parts of Pueraria lobata, 16 parts of Chuanxiong, 15 parts of red peony,

[0025] 15 parts of yam, 15 parts of scutellaria, 12 parts of Moutan bark, 10 parts of Guizhi, 10 parts of dandelion,

[0026] 10 parts of pomegranate peel, 8 parts of turmeric, 8 parts of Poria, 7 parts of dried ginger, 7 parts of pinellia,

[0027] 6 parts of Xiangfu, 6 parts of tangerine peel, 5 parts of Coptis, 5 parts of Zedoary, 4 parts of Myrrh,

[0028] 3 servings of mulberry leaf and 2 servings of mountain bean root.

[0029] The preparation process of the above-mentioned pharmaceutical composition includes the following steps:

[0030] 1) Take the salvia miltiorrhiza, fangfe...

Embodiment 2

[0035] Safety test and efficacy test of the premenstrual safe pharmaceutical composition prepared in Example 1 of the present invention:

[0036] 1. Toxicity test:

[0037] In this experiment, healthy SD rats were used. Oral administration of the drug dose gradient prepared in Example 1 was 0.1g / kg and 0.5g / kg, and the drug was administered continuously for 30 days. The rats were observed during the administration period and 1 week after the withdrawal Animal growth status, active diet, hematology, blood biochemistry, organ tissue structure and urine routine were not significantly affected, indicating that clinical medication is safe and reliable.

[0038] 2. Analgesia experiment:

[0039] Effect on the writhing response of BALB / c mice induced by acetic acid: 90 BALB / c mice, half male and half, with an average weight of 20.7g, were randomly divided into 3 groups, namely the normal saline group, the drug group of Example 1, and Control drug group (Jingqianan tablets, 0.37g / tablet, Don...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines and discloses a premenstrual ease pharmaceutical composition prepared from Chinese herbal medicines. The premenstrual ease pharmaceutical composition is prepared from radix bupleuri, radix platycodonis, arillus longan, leonurus, radix salviae miltiorrhizae, seaweed, radix saposhnikoviae, radix puerariae, szechuan lovage rhizome, radix paeoniae rubra, rhizoma dioscoreae, radish seed, cortex moutan radicis, cassia twig, herbal taraxaci, pericarpium granati, radix curcumae, poria, dried ginger, rhizoma pinelliae, rhizoma cyperi, pericarpium citri reticulatae, coptis chinensis, rhizoma curcumae, myrrha, mulberry leaf, and radix sophorae tonkinensis. The invention further discloses a preparation technique of the premenstrual ease pharmaceutical composition. The premenstrual ease pharmaceutical composition is capable of effectively treating premenstrual syndrome and has the advantages of high cure rate and low cost.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine medicines, and specifically relates to a premenstrual drug composition using Chinese herbal medicines as raw materials and a preparation process thereof. Background technique [0002] Premenstrual Syndrome (PMS) refers to a series of physical and emotional discomfort symptoms that women show in the late menstrual cycle. The symptoms have nothing to do with psychiatric and internal diseases. They are relieved in the follicular phase and spontaneously after menstruation. Return to a state without any symptoms. Its main manifestations include a series of symptoms such as irritability, insomnia, nervousness, depression, headache, breast tenderness, and facial swelling. In severe cases, it can affect women's normal life. Judging from the clinical symptoms of premenstrual syndrome, the disease is one of the diseases with a higher incidence in women of childbearing age. At the same time...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P15/00
Inventor 林凡友林凡儒
Owner XIANGYU PHARMA
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