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Method for producing tablet, and tablet

A technology for tablets and production methods, which is applied in the field of carbonic acid gas foaming composition tablets, can solve problems such as discomfort, achieve the effects of reducing the amount of addition, improving skin absorption, and improving health care and beauty effects

Inactive Publication Date: 2013-12-18
HOT ALBUM TANSANSEN TABLET
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the fine powder of metal soap generally used as a mold release agent is insoluble in water, so it may cause discomfort when using it

Method used

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  • Method for producing tablet, and tablet
  • Method for producing tablet, and tablet
  • Method for producing tablet, and tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment －1

[0123] The present invention will be described in detail through examples below, but the performance of the present invention is not limited thereto.

[0124] Granulation of raw materials for comparison

[0125] operation-1

[0126] The following operations were performed using a fluidized bed granulator GPCG-300CT produced by Powrex.

[0127] In the granulation room where the environment is adjusted to 23°C and 60%RH by air conditioning, 460kg of sodium bicarbonate is added to the fluidized bed granulator GPCG-300CT produced by Powrex and heated until the powder temperature reaches 68°C Put 80kg of PEG#6000 at the same time, and granulate after heating to 72°C. After the end, set the flowing air to 20°C to cool the powder. When the temperature of the powder reached about 35°C, the granules were taken out and put into an external airtight container, and the operation was terminated to obtain granule A01.

[0128] Similarly, the fluidized bed granulator GPCG-300CT produced b...

Embodiment －2

[0212] Operation - 9

[0213] In order to show the effective range of the present invention, the addition amount of the tablet components and the granulation conditions were changed by the following operations, and then the same following operations as in Example-1 were carried out, and the same operations as in the above-mentioned Operation-8 were carried out. The evaluation results are as follows.

[0214] Promptly add the following amount of citric acid respectively in 500kg granule A4

[0215] J12: Citric acid (300kg)

[0216] J13: Citric acid (260kg)

[0217] J14: Citric acid (150kg)

[0218] J15: Citric acid (100kg)

[0219] J16: Citric acid (60kg)

[0220] J17: Citric acid (10kg)

[0221] J18: Citric acid (5kg)

[0222] Then, 9 kg of anhydrous sodium carbonate, 10 kg of polyethylene glycol #6000 and 1.5 kg of sodium n-octane sulfonate were added to these mixtures respectively, and after mixing, they were passed through Applied Power Industry [Japan Applied Electr...

Embodiment －3

[0227] Operation - 10

[0228] With respect to the granule A4 of 500kg, add 80kg citric acid and 15kg polyethylene glycol #6000, 1.5kg n-sodium octane sulfonate and mix, take a certain amount of this mixture respectively, add different amounts of sodium carbonate to it, pass Applied The hydraulic type (manual tablet making machine) produced by Power Industry [Nippon Applied Electric Power Company] (former company name: Toyo Hydraulic Equipment Co., Ltd.: type: SPLF-SPF-393) applies a weight of 8t to these mixtures, and produces a diameter of 30mm. Tablets with a thickness of 15mm, respectively select the tablets whose pH value can reach J24=4.5J25=5.6J26=6.2J27=7.2J28=7.8J29=8.4J30=9.5 after dissolving, carry out the same evaluation as Example 3, the results are as follows shown in the table.

[0229] table 3

[0230]

[0231] It can be seen from the above results that when the pH value of the tablet after dissolution is between 5.5 and 8.5, better effects can be obtained...

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Abstract

The problem to be solved by the present invention is to provide: a method for producing a tablet, such as a carbonate-spring-type bath agent, which is so designed that a neutralization reaction can occur vigorously and efficiently in the inside of the tablet in spite of a fact that the pH value of an aqueous solution into which the tablet is dissolved is neutral, carbon dioxide gas bubbles having as small sizes as possible can be released continuously for a certain period of time and therefore a large portion of the generated carbon dioxide gas can be dissolved in water without dissipating the carbon dioxide gas to air to thereby increase the total concentration of carbon dioxide components in water, and the carbon dioxide gas that contacts with the skin can be converted into a bicarbonate ion readily due to the pH value of the aqueous solution so that the bicarbonate ion can be absorbed through the skin; and the tablet. The solution for the problem is a method for producing a tablet by carrying out compression molding in the presence of an organic acid in an amount of 1 / 10 to 1 / 3 of the amount of a bicarbonate salt (sodium bicarbonate or potassium bicarbonate) and polyethylene glycol in an amount of 1 / 100 to 1 / 5 of the amount of the bicarbonate salt, wherein the tablet is produced by compression molding in such a manner that an aqueous solution in which the tablet is dissolved can have a pH value of 5.5 to 8.5, the hardness of the tablet becomes 15 kg or more, and each of the diameter and the thickness direction of the tablet becomes 7 mm or more.

Description

technical field [0001] The present invention relates to a tablet of a carbonic acid gas foaming composition and a method for making the tablet. Specifically, bicarbonate and organic acid are mixed according to a certain ratio to make a tablet with a certain hardness for use as a bathing additive. When the tablet is dissolved in hot water (in the present invention, hot water refers to water or hot water heated to emit steam or a mixture of both.), the pH of the aqueous solution will be maintained in the range of 5.5 to 8.5 . High-hardness tablets will create an environment in which carbon dioxide bubbles are continuously and violently generated, and the diameter of the carbon dioxide bubbles can be controlled below a certain level to generate micro-sized bubbles, thereby increasing the surface area of ​​the bubbles and making the carbon dioxide solubility of hot water leap. sexual enhancement. At the same time, the foaming can be carried out slowly and continuously inside th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/86A61K8/362A61K8/19A61K8/02A61Q19/10
CPCA61K8/0216A61K8/19A61K8/365A61K8/86A61K9/1641A61K9/2009A61K9/2013A61K9/2031A61K9/2095A61K2800/222A61Q19/10A61K33/00
Inventor 小星重冶吉本博
Owner HOT ALBUM TANSANSEN TABLET
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