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Composition comprising peroxisome proliferator-activated receptor-gamma

A technology of peroxisome and composition, applied in the field of injectable compositions, can solve the problems of complexity, high price, inconvenience and the like

Inactive Publication Date: 2013-12-11
MERZ PHARMA GMBH & CO KGAA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, fillers of synthetic or animal origin may cause hypersensitivity reactions
The process of autologous fat injection to transfer a patient's fat from one location to another is very complicated, expensive and invasive treatment that also needs to be matched with the right timing, which is inconvenient for the patient

Method used

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  • Composition comprising peroxisome proliferator-activated receptor-gamma
  • Composition comprising peroxisome proliferator-activated receptor-gamma
  • Composition comprising peroxisome proliferator-activated receptor-gamma

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Embodiment Construction

[0019] The present invention provides an injectable composition comprising peroxisome proliferator-activated receptor-gamma for subcutaneous administration. The composition of the present invention has good bioavailability, induces sustainable production (regeneration) of natural fat, and does not have any strong invasiveness. In addition, side effects can be reduced compared to existing fillers. Furthermore, a more natural appearance can also be formed. The compositions of the present invention may act as fillers or body plasticizers. Furthermore, by using a natural compound (the injectable composition) compared to synthetic or animal-derived fillers, there is consistent tolerability and safety. Therefore, an allergic reaction is unlikely. In addition, it is convenient and more effective for patients.

[0020] The beneficial effects of the composition are believed to be due to the reaction of peroxisome proliferator-activated receptor-gamma with adipocytes. Peroxisome pr...

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Abstract

The invention relates to an injectable composition comprising peroxisome proliferator-activated receptor-gamma used for subcutaneous administration, and a method for improving skin imperfections. The injectable composition is subcutaneously administered at an area of the skin imperfections by steps of a) identifying the area of the skin imperfections, and b) administering a safe and cosmetically effective amount of the composition subcutaneously to the area of the skin imperfections by subcutaneous administration or subdermal administration.

Description

technical field [0001] The present invention relates to an injectable composition comprising peroxisome proliferator-activated receptor-gamma for subcutaneous administration. The present invention also relates to the use of a composition for improving skin imperfections. Furthermore, the present invention also relates to a method for improving skin defects. Wherein, the injectable composition comprising peroxisome proliferator-activated receptor-γ is subcutaneously administered to the area of ​​skin defect, comprising the steps of: a, identifying the area of ​​skin defect; b, subcutaneously or dermally administering A safe and cosmetically effective amount of the composition is applied to the area of ​​the skin imperfection. Background technique [0002] The skin is a complex tissue that is generally divided into three main layers, the epidermis, the dermis, and the subcutaneous tissue beneath the dermis. The deepest layer of the skin contains fat cells, also known as the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/02A61K8/66A61Q19/06A61Q19/08C07K14/705
CPCA61K2800/78A61K2800/86A61K2800/91A61Q19/06A61Q19/08C07K14/70567A61K8/64A61P17/00A61P17/02A61P29/00A61P43/00A61K8/66A61K8/02C07K14/705A61Q19/00
Inventor H·巴格R·波特
Owner MERZ PHARMA GMBH & CO KGAA
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