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Cooling paste for children and preparation method thereof

An antipyretic patch and children's technology, applied in the field of medicine, can solve the problems of small adhesion, poor skin affinity, inferior quality and performance, etc., and achieve the effect of good effect, scientific and reasonable components, and convenient use

Inactive Publication Date: 2013-10-23
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the children's antipyretic patches on the Chinese market are purely physical cooling, and the quality and performance of domestic products are not as good as those of foreign-funded enterprises. They have disadvantages such as poor skin affinity, weak adhesion and easy to fall off.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] In the specific implementation of the present invention, it is calculated by the following weight percentages: sodium polyacrylate 12.5-13.5%, edible gelatin 2.5-6%, carboxymethyl cellulose sodium 4-7%, citric acid 0.65-0.8%, calorie Boomer 10-20%, astragalus polysaccharide 2.5-5.5%, Bupleurum distillate 14-16%, kaolin or diatomaceous earth 9.5-10.5%, glycerin 26-35%, propylene glycol 7.5-10.5%, menthol 1.5-6 % and disodium edetate 0.08-0.22% as raw materials, of which:

[0014] (1) Dissolve disodium edetate with 50 times its weight in water to form a disodium edetate aqueous solution, add carbomer to swell with 2.5 times its weight in water, then add edetate di Sodium aqueous solution, adjust the pH value to 7.0-9.0 with sodium hydroxide or triethanolamine to obtain disodium edetate and carbomer swelling solution; add 3-5 times the weight of water to edible gelatin, 35-60 Dissolve at ℃ to get gelatin solution; add astragalus polysaccharide to dissolve in water 5-10 ti...

Embodiment 2

[0018] In the specific implementation of the present invention, it is calculated by the following weight percentages: sodium polyacrylate 11%, edible gelatin 6.2%, carboxymethyl cellulose sodium 3.16%, citric acid 0.4%, carbomer 26%, astragalus polysaccharide 6% %, Bupleurum distillate 10%, kaolin or diatomite 11%, glycerin 20%, propylene glycol 6%, menthol 0.2% and disodium edetate 0.04% as raw materials, of which:

[0019] (1) Dissolve disodium edetate with 50 times its weight in water to form a disodium edetate aqueous solution, add carbomer to swell with 2.5 times its weight in water, then add edetate di Sodium aqueous solution, adjust the pH value to 7.0-9.0 with sodium hydroxide or triethanolamine to obtain disodium edetate and carbomer swelling solution; add 3-5 times the weight of water to edible gelatin, 35-60 Dissolve at ℃ to get gelatin solution; add astragalus polysaccharide to dissolve in water 5-10 times its weight to get astragalus polysaccharide solution; add g...

Embodiment 3

[0023] In the specific implementation of the present invention, it is calculated by the following weight percentages: sodium polyacrylate 14%, edible gelatin 2.2%, sodium carboxymethyl cellulose 5%, citric acid 1%, carbomer 7%, astragalus polysaccharide 4% %, Bupleurum distillate 12%, kaolin or diatomite 8%, glycerin 30%, propylene glycol 10%, menthol 6.6% and disodium edetate 0.2% as raw materials, of which:

[0024] (1) Dissolve disodium edetate with 50 times its weight in water to form a disodium edetate aqueous solution, add carbomer to swell with 2.5 times its weight in water, then add edetate di Sodium aqueous solution, adjust the pH value to 7.0-9.0 with sodium hydroxide or triethanolamine to obtain disodium edetate and carbomer swelling solution; add 3-5 times the weight of water to edible gelatin, 35-60 Dissolve at ℃ to get gelatin solution; add astragalus polysaccharide to dissolve in water 5-10 times its weight to get astragalus polysaccharide solution; add gelatin ...

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Abstract

The invention relates to a cooling paste for children and a preparation method thereof, and solves treatment and medication problems for children having a fever. The technical scheme is that the cooling paste is prepared from raw materials, by weight, comprising 10-14% of sodium polyacrylate, 2.2-6.2% of edible gelatin, 2-8% of sodium carboxymethylcellulose, 0.4-1% of citric acid, 4-26% of carbomer, 2-6% of astragalus polysaccharides, 10-20% of a distillate of the root of Chinese thorowax, 8-11% of kaolin or diatomite, 20-40% of glycerin, 6-12% of propylene glycol, 0.2-6.6% of menthol and 0.04-0.24% of disodium dihydrogen ethylenediaminetetraacetate. The cooling paste has advantages of scientific and reasonable components, abundant raw materials, easy production, usage convenience and good effects. The cooling paste can be effectively used for treating the children having a fever, and is an innovation in medicines used for treating the children having a fever.

Description

technical field [0001] The invention relates to medicine, in particular to an antipyretic plaster for children and a preparation method thereof. Background technique [0002] Fever in children is a common and frequently-occurring disease. If it is not treated in time, it will affect the health of children. Maintaining a normal body temperature is a very complicated physiological and chemical process. The main heat dissipation site of the human body is the skin. In the hot summer season, children are prone to "heat syndrome" mainly due to fever symptoms due to their immature physical development and poor body temperature regulation ability. In addition, the normal response of the autoimmune system to protect itself when a child is infected by a pathogen can also cause fever. At present, most of the antipyretic plasters for children in the Chinese market are purely for physical cooling, and the quality and performance of domestic products are not as good as those of foreign-...

Claims

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Application Information

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IPC IPC(8): A61K36/233A61K9/70A61K47/42A61P29/00A61K31/715A61K31/045
Inventor 冯素香刘富岗杨云胡亚楠
Owner HENAN UNIV OF CHINESE MEDICINE
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