Dynamic micro-sensor detecting system

Abstract

The invention belongs to a dynamic micro-sensor detecting system which is extensively applied to the technical fields of dynamic monitoring on important ingredients of serious diseases, such as neuropsychiatric diseases and diabetes, and biological chip preparation by dynamic DNA synthesis, and the like. The dynamic micro-sensor detecting system comprises a flow cell, a flowing pool, a sensor supporting body and a sensor. On one hand, the system is capable of ensuring full reaction, timely removal of raffinate and convenient assembly, disassembly and clean in a monitoring process under dynamic conditions, on the other hand, selected working electrodes are formed by a modified porous electrode supporting plate with high sensitivity and selectivity on a detected object, thereby being beneficial to change of the electrodes, and adding new serially connected working electrodes to simultaneously detect a plurality of ingredients. The detecting system is beneficial to realize on-line, real-time and quick monitoring and is beneficial to improving the stability, sensitivity and selectivity of a detecting signal in dynamic detection.

Description

technical field [0001] This patent belongs to the dynamic microsensor monitoring system widely used in the technical fields of neuropsychiatric diseases, diabetes and other major diseases such as dynamic monitoring of important components, dynamic DNA synthesis and preparation of biochips, etc., especially related to the improvement of flow cells and the design and preparation of sensors. Background technique [0002] The 21st century is the century of life sciences. How to realize the in vivo, real-time and continuous detection of trace and ultra-trace biological samples, and the preparation of biochips to detect DNA mutations are of great significance to the development of biology, medicine and even life sciences. For organisms, it is of great significance to measure the dynamic changes of neurotransmitters in neuropsychiatric patients and blood sugar in diabetics: ①It can judge whether the function of certain organs of the body is normal. ② The patient's disease can be ch...

AI Technical Summary

Problems solved by technology

However, because there must be a certain distance between the working end of the sensor and the bottom of the groove, and because the flow rate of the inflowing liquid is slowed down by the resistance of the sensor, the inconsistency of the liquid level in the groove will lead to uneven response of the working end of the sensor, and the measurement results will be uneven. fluctuate, unstable

And due to the reason of the groove itself, the flow rate of the solution slows down, and the removal of residual liquid slows down. When new liquid flows in, the residual liquid is emptied, which delays the time when the measurement reaches the baseline, so the signal detected at another time point may not be The signal at the time point of the living body itself will overlap with the signal at different time points, and it is impossible to study the dynamic change information of key chemical components in the living body at different time periods and the impact and harm brought by different concentrations to the living body, let alone Realize online and real-time monitoring

[0005] The structure of a general microsensor is to assemble the working electrode, reference electrode and auxiliary electrode together. There is a problem here. If there is a problem with the working electrode, the entire electrode can only be discarded, and if you want to detect several components, you cannot add it. working electrode in series

Images