A kind of pathological automatic dna staining system and staining method

Abstract

The invention relates to a pathological automatic DNA (deoxyribonucleic acid) staining system. The system comprises a staining platform, a bearing frame, a shifting device and a mechanical arm, wherein a row of liquid tanks are embedded into the staining platform; the bearing frame is vertically connected with the staining platform; the shifting device is connected with the bearing frame in parallel; the mechanical arm is connected with the moving device in a sliding manner, and a mounting device is connected to the mechanical arm; a plurality of staining frames are hung at the lower end of the mounting device; a vent hole is formed in the bearing frame; each device is controlled to work by a microcomputer system, and a control window of the microcomputer system is formed in the side surface of the staining platform; and an air exhaust system and a power-off protection system are arranged in the pathological automatic staining system. By utilizing the technical scheme provided by the invention, the automatic operation of multiple sets of staining methods is realized, the staining is simple and stable, and the number of sheets stained once can be selected according to requirements, thus being suitable for requirements of different users.

Description

technical field [0001] The invention relates to the field of pathological detection, in particular to a device and a staining method for automatic DNA staining of glass slides submitted for pathological inspection. Background technique [0002] In recent years, with the rapid development of computer science, the quantitative analysis technology of pathological images has been widely used in medical diagnosis. Among them, the representative technology of quantitative analysis of cell DNA is of great significance to the early detection of tumors, the prognosis of cancer and the guidance of clinical treatment. The principle is to use Feulgen staining method to stain the nuclear DNA on cell smears, tissue sections or prints, that is, fix with fixative solution, hydrochloric acid acid hydrolysis, stain with Thionin staining solution or Schiff reagent, and pass through the high-precision CCD on the microscope. The camera collects the DNA image of the cell nucleus, and digitally c...

AI Technical Summary

Problems solved by technology

Almost all known pathological automatic staining machines have problems such as single staining function, poor corrosion resistance, poor washing effect, and poor practicability.

[0004]At the same time, the current Feulgen staining method takes a long time, and the time points of each step need to be specially recorded, which is not conducive to the pathological technician to arrange other work

Manual operation, the dye solution is often not conducive to reuse, and it is easy to expose the skin to strong corrosive gases, which is a great health threat to pathologists

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