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Assembly to facilitate user reconstitution

A technology of components and kits, applied in special packaging objects, packaged food, packaging, etc., can solve problems such as difficulties for patients or medical staff during the reorganization process

Active Publication Date: 2013-06-12
TAKEDA PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If air is allowed to enter the interior of the bottle before the diluent is injected, this can make the reconstitution process more difficult for the patient or healthcare provider
[0005] Therefore, reconstitution presents challenges in ensuring product sterility and providing ease of use to patients or healthcare professionals

Method used

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  • Assembly to facilitate user reconstitution
  • Assembly to facilitate user reconstitution
  • Assembly to facilitate user reconstitution

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0034] The present disclosure provides recombination components particularly useful for reconstituting lyophilized pharmaceuticals. While the assembly is primarily described herein with reference to the reconstitution of lyophilized pharmaceuticals, it will be apparent that the assembly can be used to reconstitute other materials.

[0035] Referring now to the attached drawings and specifically to figure 1 and 2 , a recombination assembly 10 is shown. Assembly 10 includes a housing 12 . Housing 12 maintains alignment and restricts movement of internal components. Housing 12 includes a first or lower sleeve 20 and a second or upper sleeve 30 and defines a generally cylindrical interior passage 11, and at least a portion of a second container 80 is disposed between first or lower sleeve 20 and Channel 11. Housing 12 may be surrounded by packaging during storage and transport.

[0036] Transfer Kit 40 ( figure 2 ) is disposed within the housing 12 and fixed between the co...

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Abstract

A reconstitution assembly includes a housing including a lower sleeve and an upper sleeve, including a first container and a second container disposed vertically opposite the first container. A transfer set assembly is disposed within the housing between the first container and the second container. The transfer set assembly includes an upper spike housing and a lower spike housing, with a flow path defined through the upper spike housing and the lower spike housing. The transfer set assembly is configured to access contents of the first container and then upon the activation of a triggering mechanism, create a fluid pathway between the first container and the second container. The triggering mechanism includes trigger fingers which ensure the transfer set assembly sequentially accesses the contents of the first container before accessing the contents of the second container. The disposition of the first container activates the triggering mechanism.

Description

Background technique [0001] This disclosure is primarily concerned with recombining components. More specifically, the present disclosure relates to drug reconstitution assemblies for reconstituting lyophilized drugs. [0002] Some medicines are available in lyophilized form. A lyophilized drug must be mixed with water to reconstitute the drug into a form suitable for injection into a patient. Specifically, all parts that come into contact with the drug must be sterilized to avoid the possibility of infection. [0003] This restructuring process can be difficult for people who need to inject themselves or other family members in a home setting. This general process requires precise, continuous manipulation of vials, dilution containers and transfer syringes, which necessitates the use of a needle to pierce the vial stopper. This procedure should be done with good aseptic practice. [0004] In addition, many lyophilized drugs are placed in vials that have a negative intern...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J1/20
CPCA61J1/2089A61J1/2065A61J1/2075A61J1/2082A61J1/2013A61J1/201A61J1/1406A61J1/2086
Inventor 斯科特·阿里阿基诺弗雷德里克·查尔斯·霍顿二世丹尼尔·E·鲁斯
Owner TAKEDA PHARMA CO LTD
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