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Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source

A source and population technology, applied in biochemical equipment and methods, microbial determination/inspection, etc., can solve the problem of no Uyghur population research and other issues

Active Publication Date: 2013-06-12
INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no research on Chinese Han, Tibetan, and Uyghur populations

Method used

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  • Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source
  • Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source
  • Method and system used for deducing Han, Tibetan or Wei population source of individual with unknown source

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] In Example 1, 192 unrelated individual DNA samples were used for testing, among them: 92 individuals of the Han nationality (40 males; 52 females), 50 Tibetans (23 males; 27 females), 50 Uighurs (20 males ; female 30),

Embodiment 2

[0068] What used in embodiment 2 is the DNA sample of 3 known Han, Tibetan, Uighur groups randomly screened in 192 individuals

Embodiment 3

[0069] 135 individual test samples (one for each individual) used in embodiment 3 are from the specific sources of Han nationality, Tibetan nationality and Uighur nationality:

[0070] Types of

source

Quantity (parts)

Numbering

[0071] Han DNA samples

Cases in this laboratory

12

1-12

Han nationality venous blood

volunteer

33

13-45

Uighur blood spot samples

Bingtuan Public Security Bureau

12

46-57

Uighur blood

volunteer

33

58-90

Tibetan blood spot samples

Cases in this laboratory

12

91-102

Tibetan blood

volunteer

33

103-135

[0072] Among them, 12 Uighur blood spot samples were provided by Xinjiang Corps Public Security Bureau, 12 Tibetan blood spot samples and 12 Han blood spot samples were provided by the Physical Evidence Identification Center of the Ministry of Public Security.

[0073] Genomic DNA from venous blood was se...

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PUM

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Abstract

The invention provides a method and a system used for deducing the Han, Tibetan or Wei population source of an individual with an unknown source. The method comprises the following steps: detecting DNA of the individual with an unknown source to obtain genotypes of 94 specific sites of Han, Tibetan and Wei populations; acquiring genotype frequencies of each specific site of the individual with an unknown source in Han, Tibetan and Wei populations respectively; multiplying the genotype frequencies of each specific site to obtain coupling probability values of the 94 specific sites in Han, Tibetan and Wei populations respectively; and determining a population with a highest coupling probability value as a source population of the individual with an unknown source. With the method and the system in the invention, high accuracy deduction of a Han, Tibetan or Wei population source can be realized.

Description

technical field [0001] The present invention relates to a method and a system for inferring the origin of an individual of unknown origin, in particular to a method and a system for inferring the origin of an individual of unknown origin in Han, Tibetan, and Uighur groups. Background technique [0002] With the continuous improvement of the scientific, objectivity and accuracy requirements of judicial litigation activities, the field of physical evidence identification continues to develop, requiring more accurate analysis methods to determine the individual source of inspection materials in cases, DNA analysis Because of its accurate test results, it has become an important technical means in the field of physical evidence identification. [0003] Current forensic DNA analysis usually involves autosomal or Y chromosome tandem repeat (STR) detection, or mitochondrial sequencing and analysis of on-site biological evidence, such as blood, hair, cigarette butts, and semen spots...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68
Inventor 李彩霞魏以梁胡兰季安全贾竟李万水
Owner INST OF FORENSIC SCI OF MIN OF PUBLIC SECURITY
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