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Application of nymphaea hybrid or product thereof

A technology of lotus perfume and products, applied in the field of improving prostate symptoms, can solve the problems of severe muscle disease, impaired muscle growth, strong side effects, etc., achieve significant 5α-reductase activity and inhibit 5α-reductase activity

Active Publication Date: 2013-05-15
浙江芸麒龙祥生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In the past 20 years, many steroidal and non-steroidal competitive, non-competitive or anti-competitive 5α-reductase inhibitors have been discovered and synthesized. For example, benzoquinone can strongly inhibit 5α-reductase in vivo and in vitro Function, finasteride has been used as a conventional drug for the treatment of benign prostatic hyperplasia, but these inhibitors have strong side effects, such as feminization of male breasts, impaired muscle growth, severe muscle diseases, etc.

Method used

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  • Application of nymphaea hybrid or product thereof
  • Application of nymphaea hybrid or product thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1, a kind of preparation method of lotus extract, carries out following steps successively:

[0040] 1) Crush the dried lotus flower (water content ≤ 8%) until it can pass through a 40-mesh sieve to get the lotus powder;

[0041] 2) Add 200mL of 50% ethanol aqueous solution to the above 10g of lotus powder, heat and reflux for extraction, the extraction time is 1h; suction and filter under reduced pressure (0.09MPa) while it is hot, and obtain the first filtrate and filter residue respectively;

[0042] Repeat the above extraction of the filter residue: add 200mL of 50% ethanol aqueous solution to the filter residue, heat and reflux for extraction, the extraction time is 1h; while it is hot, vacuum filter (0.09MPa) to obtain the secondary filtrate;

[0043] That is, the number of times of extraction is two in total.

[0044] 3) Combine the first filtrate and the second filtrate to obtain about 350mL of the lotus extract solution;

[0045]The above saponin e...

Embodiment 2

[0046] Embodiment 2, a kind of preparation method of lotus extract, carries out following steps successively:

[0047] 1) Crush the dried lotus flower (water content ≤ 8%) until it can pass through a 40-mesh sieve to get the lotus powder;

[0048] 2) Add 200mL of distilled water to the above 10g of lotus powder for ultrasonic extraction (frequency of 50Hz, power of 600W), the extraction time is 1h; suction filtration under reduced pressure (0.09MPa) to obtain the first filtrate and filter residue respectively;

[0049] Repeat the above extraction twice with the filter residue; that is, replace the lotus powder with the filter residue to extract according to the above process conditions;

[0050] That is, the number of times of extraction is three times in total.

[0051] 3) Combine the first filtrate and the filtrate obtained from the last two extractions to obtain about 530mL of saponin extract solution;

[0052] Concentrate (concentrate to 1 / 10 of the original volume at 50...

Embodiment 3-1

[0053] Embodiment 3-1, a kind of preparation method of fragrant lotus wine, take fragrant lotus flower as raw material, carry out the following steps successively:

[0054] Get 0.1 kg of white sugar and add 0.9 kg of pure water to obtain sugar water with a mass concentration of 10% after dissolving. After removing the receptacle, take 1 kg of fragrant lotus flowers, wash and dry the surface water, tear the petals and put them in a pottery container, add 1 kg of 10% sugar water, cover (seal) and soak for 48 hours, then add 8 45% (alcohol) commercially available Site wine is sealed and soaked for 45 days, filtered to remove flower residue, and the obtained filtrate is put into a pottery container, sealed and stored at room temperature for 6 months to obtain the finished product - Xianglian wine .

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Abstract

The invention relates to application of nymphaea hybrid or a product thereof, and specifically relates to application of nymphaea hybrid to improvement of prostate symptoms. Specifically, the invention discloses the application of a nymphaea hybrid or a product thereof to preparation of medicament or health care product for improving symptoms of prostate. Improvements of the symptoms of prostate involve treatment of prostatic hyperplasia or prevention of prostatitis; the nymphaea hybrid product is a nymphaea hybrid extract or a nymphaea hybrid wine; and the nymphaea hybrid refers to dried flower or fresh flower of nymphaea hybrid. The invention conducts systematic studies on effects of nymphaea hybrid and product thereof on prevention of 5 alpha-reductase related diseases, especially prevention of prostate hyperplasia; and results show that nymphaea hybrid and product thereof have obvious effects on 5 alpha-reductase activity inhibition and prostatic hyperplasia resistance.

Description

technical field [0001] The present invention relates to the use of perfumed lotus (abbreviated as fragrant lotus) and perfumed lotus products, in particular to its use in improving prostate symptoms. Background technique [0002] Prostatic hyperplasia (BPH), also known as prostatic hypertrophy, is a disease caused by benign adenomatous hyperplasia of the interstitial cells around the prostatic urethra, which narrows the prostatic urethra and causes bladder outlet obstruction. Lower urinary tract symptoms (LUTS) such as waiting, nocturia, and urinary interruption, and serious complications include recurrent urinary tract infections, acute urinary retention, bladder stones, and renal failure. [0003] The prevalence of benign prostatic hyperplasia is positively correlated with age. From the perspective of histology, it generally begins to appear at the age of 40, the prevalence rate exceeds 50% at the age of 60, and the prevalence rate reaches 90% at the age of 85. [0004] B...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/62A61P13/08A23L1/29A23L33/00
Inventor 沈建福芦芳车璐吴晓琴
Owner 浙江芸麒龙祥生物技术有限公司
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