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Method for producing omphalia lapidescens schroet tables

A production method, the technology of Leiwan Tablets, is applied in the direction of sugar-coated pills, pill delivery, blood diseases, etc., and can solve the problems of reducing curative effect, easy moisture absorption, instability, etc.

Inactive Publication Date: 2013-05-15
GUANGXI BAIQI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide the preparation method of Lei Wan tablet, overcomes the deficiency that existing Lei Wan preparation is easy to absorb moisture, is unstable and reduces curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] (1) Take 300 grams of dried Chinese medicine Leiwan, soak in 90 grams of 1.8% sodium chloride solution, until the Chinese medicine Leiwan completely absorbs the soaking solution, and dry it at 80-100°C for 18 hours to obtain dry Leiwan for later use ;

[0017] (2) Get the above-mentioned dried thunder pills and pulverize them into 200 mesh fine powder for subsequent use;

[0018] (3) Get above-mentioned Lei Wan fine powder and mix evenly with 75 grams of sugar powder, 15 grams of dextrin, 15 grams of sodium hydroxymethyl starch, granulate with 50% syrup, and press the whole grain into tablets.

[0019] (4) Use gastric-soluble pharmaceutical film-coating premixed auxiliary materials as the coating material, and coat the above-mentioned Lei Wan tablets with film-coating.

Embodiment 2

[0021] (1) Take 300 grams of dried Chinese medicine Leiwan, soak in 200 grams of 3.0% sodium chloride solution, until the Chinese medicine Leiwan fully absorbs the soaking liquid, and dry it at 80-100°C for 20 hours to obtain dry Leiwan for later use ;

[0022] (2) Get the above-mentioned dried thunder pills and pulverize them into 300 mesh fine powder for subsequent use;

[0023] (3) Get above-mentioned Lei Wan fine powder and mix evenly with 75 grams of sugar powder, 15 grams of dextrin, 15 grams of sodium hydroxymethyl starch, granulate with 50% syrup, and press the whole grain into tablets.

[0024] (4) Use gastric-soluble pharmaceutical film-coating premixed auxiliary materials as the coating material, and coat the above-mentioned Lei Wan tablets with film-coating.

Embodiment 3

[0026] (1) Take 300 grams of dried Chinese medicine Leiwan, soak in 200 grams of 2.5% sodium chloride solution, until the Chinese medicine Leiwan completely absorbs the soaking solution, and dry it at 80-100°C for 15 hours to obtain dry Leiwan for later use ;

[0027] (2) Get the above-mentioned dried thunder pills and pulverize them into 300 mesh fine powder for subsequent use;

[0028] (3) Get above-mentioned Lei Wan fine powder and mix evenly with 75 grams of sugar powder, 15 grams of dextrin, 15 grams of sodium hydroxymethyl starch, granulate with 50% syrup, and press the whole grain into tablets.

[0029] (4) Use gastric-soluble pharmaceutical film-coating premixed auxiliary materials as the coating material, and coat the above-mentioned Lei Wan tablets with film-coating.

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Abstract

The invention discloses a method for preparing omphalia lapidescens schroet tables. The traditional Chinese medicine omphalia lapidescens schroet is the sclerotium of the polyporaceae plant omphalialapidescens; and proved by lots of clinical applications, the traditional Chinese medicine omphalia lapidescens schroet has functions of obviously increasing white blood cells, enhancing the immunity of the organism, preventing thymic atrophy and the like. Therefore, the traditional Chinese medicine preparation prepared from the omphalia lapidescens schroet is effective for assistant treatment of cancer. However, the omphalia lapidescens schroet has the characteristic of hygroscopicity, the preparation prepared from the omphalia lapidescens schroet will be unstable due to the hygroscopicity; therefore, the curative effect is reduced and undesirable effects may be generated. The preparation prepared by the method disclosed by the invention is proved to have excellent stability through long-term tests and acceleration tests, quantitative determination with bovine serum albumin as the content detection index and the detection of other necessary quality indexes carried out simultaneously.

Description

technical field [0001] The invention relates to a production method of Thunder Pill Tablets, belonging to the technical field of traditional Chinese medicine preparations. Background technique [0002] Malignant tumors are clinically treated with chemical drugs and radiotherapy with Y or X-rays. Most chemical anticancer drugs have considerable toxicity, and the first damage is the white blood cells in the hematopoietic system. Leukocytes are important immune cells of the human body. Once the human leukocytes drop below 1.0×109 / L, they may be infected by other pathogens and cause serious consequences. The traditional Chinese medicine Leiwan is the sclerotium of the plant Leiwan of Polyporaceae. A large number of clinical applications have proved that it has the functions of obviously increasing white blood cells, enhancing the body's immunity, and preventing thymus atrophy. Therefore, it is effective to use Lei Wan to prepare traditional Chinese medicine preparations for adj...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/06A61K9/28A61P7/00A61P35/00A61P37/04
Inventor 陈越陈萍梁菊芬
Owner GUANGXI BAIQI PHARMA
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