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Compound coptis chinensis liquid

A technology of Coptis chinensis and compound recipes, applied in the field of compound Coptis chinensis liquid, can solve the problems of ineffectiveness of disease-resistant factors, reduced curative effect, and difficulty in obtaining it, and achieve the effects of easy storage and promotion, reduced production costs, and a wide range of applications

Active Publication Date: 2013-04-24
蒋顺琬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the application of antibiotics plays a large role in the treatment of chronic osteomyelitis, long-term use will often reduce the efficacy due to the development of drug resistance
In addition, due to pathological changes such as the fibrosis of the surrounding tissue of the chronic osteomyelitis lesion and the existence of sequestrum and dead space, the local blood supply is poor, which not only makes the effective concentration of antibiotics in the lesion less than the effective concentration, but also affects the body's immune system and other diseases. Anti-disease factors do not play an effective role
Although local application of antibiotics can increase the concentration of antibiotics in the lesion by several times to dozens of times, thus playing an effective antibacterial effect, but at the same time inhibits the growth and filling of granulation tissue, which is not conducive to wound repair
In recent years, due to the progress of microsurgical techniques, tissue transplantation is used to eliminate bone exposure and improve local blood supply to improve curative effect, but the failure rate of this type of operation is also high
[0003] In addition, TCM external treatment is the characteristic of TCM treatment of chronic osteomyelitis, but most of the important preparations such as creams, pills, pills, and powders are not only complicated to make, but most of the drugs used are rare and precious medicinal materials, which are not easy to obtain
On the one hand, solid dosage forms limit the contact area with the lesion, which is not conducive to exerting therapeutic effects; on the other hand, foreign bodies may be left in the local area, which is not conducive to treatment

Method used

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  • Compound coptis chinensis liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Take 90g of Coptis chinensis, 30g of Scutellaria baicalensis, 30g of Cortex Phellodendri, 30g of Gardenia, 30g of Burnet, 30g of Rhubarb, and 30g of Astragalus.

[0021] Add 3L of water, extract at 100°C for 2 hours, filter out medicinal solution A for later use;

[0022] Take the dregs, add 2.5L of water, extract at 100°C for 2 hours, and filter out the medicinal solution B for later use;

[0023] Combine the medicinal liquids A and B, concentrate to a temperature of 80°C, and a relative density of 1.2. After cooling to room temperature, add 10 g of borneol and 5 L of ethanol, stir, let it stand, take the supernatant, recover the ethanol and add purified water to obtain 6 L of compound coptis liquid ;

[0024] Take the compound Coptis chinensis liquid, apply it to the affected area, and change the dressing every other day until the disease is cured.

Embodiment 2

[0026] Take Coptidis 95g, Scutellaria baicalensis 28g, Phellodendron 30g, Gardenia 28g, Burnet 30g, Rhubarb 32g, Astragalus 30g;

[0027] The preparation method is the same as in Example 1 to obtain compound Coptis chinensis liquid, which is used to wet compress the affected area.

Embodiment 3

[0029] Take Coptidis 88g, Scutellaria baicalensis 30g, Phellodendron 32g, Gardenia 28g, Burnet 32g, Rhubarb 32g, Astragalus 30g;

[0030] The preparation method is the same as in Example 1 to obtain compound Coptis chinensis liquid, which is used to wet compress the affected area.

[0031] In order to objectively evaluate the clinical effects of the present invention, from May, 1991 to May, 1995, chronic osteomyelitis cases were randomly divided into a compound coptis liquid external application group of the present invention (hereinafter referred to as a treatment group) and a gentamicin solution external application group (hereinafter referred to as a treatment group). called the control group). The curative effect of each group was evaluated according to the unified curative effect standard, and the results were as follows:

[0032] 1. Diagnostic criteria

[0033] (1) History of trauma infection, local soft tissue infection or acute hematogenous osteomyelitis;

[0034] (...

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Abstract

The invention relates to the field of traditional Chinese medicine, and discloses a compound coptis chinensis liquid which is prepared by using coptis chinensis, scutellaria baicalensis, golden cypress, jasmine, garden burnet, rheum officinale, astragalus mongholicus and borneol as raw materials and boiling in water and extracting. The compound coptis chinensis liquid has a good effect in treating chronic osteomyelitis and acute soft tissue injury, reduces the production cost, is simple and convenient to use, wide in application range and convenient to store and popularize.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a compound coptis liquid for treating chronic osteomyelitis and acute soft tissue injury. Background technique [0002] Chronic osteomyelitis is one of the difficult diseases in orthopedics and traumatology. It belongs to the category of "attached gangrene" in traditional Chinese medicine. The main methods of existing traditional Chinese and Western medicine treatment of chronic osteomyelitis include the application of antibiotics, surgical treatment, and improving the body's resistance by improving the general condition. Although the application of antibiotics plays an important role in the treatment of chronic osteomyelitis, long-term use will often reduce its efficacy due to the development of drug resistance. In addition, due to pathological changes such as the fibrosis of the surrounding tissue of the chronic osteomyelitis lesion and the existence of s...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P7/00A61P29/00A61K31/045
Inventor 陆杰蒋顺琬
Owner 蒋顺琬
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