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Compound skin disinfectant and preparation method thereof

A disinfectant and skin technology, applied in the field of composite skin disinfectant and its preparation, can solve the problem that skin disinfectant has no persistent activity, and achieve the effect of promoting wound healing, good stability and convenient use

Inactive Publication Date: 2013-04-24
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to solve the problem that existing skin disinfectants do not have persistent activity, the invention provides a compound skin disinfectant with persistent bactericidal effect and its preparation method

Method used

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  • Compound skin disinfectant and preparation method thereof
  • Compound skin disinfectant and preparation method thereof
  • Compound skin disinfectant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Mix 60g Cnidium Fructus Cnidii, 60g Sophora Sophora, 40g Coptidis Rhizome, 30g Kuding, 100g Honeysuckle, 150g Licorice, and 90g Comfrey, add 5kg of water to decoct for 3 hours, filter to obtain the filtrate; concentrate the filtrate, dry at room temperature, grind , vested powdery component A;

[0050] Take 5g of component A, add 5g of deionized water, stir, and wait until component A is completely dissolved to obtain an aqueous solution;

[0051] Get 15g dehydrated alcohol, add 2g camphor wherein, treat that after camphor dissolves completely, add 1g part of Fructus Cnidii ethanol extract, 0.6g Asarum ethanol extract, 0.8g lavender volatile oil, 0.2g Asarum volatile oil, make each component Completely miscible to obtain ethanol;

[0052] Under the condition of stirring, slowly add the ethanol agent into the aqueous solution, and then add 0.1 g of hyaluronic acid, and mix evenly to obtain the product.

Embodiment 2

[0054] Mix 60g Cnidium Fructus Cnidii, 90g Sophora Sophora, 20g Coptidis Rhizome, 50g Kuding, 120g Honeysuckle, 150g Licorice, and 100g Comfrey, add 3kg of water to decoct for 5 hours, filter to obtain the filtrate; concentrate the filtrate, dry at room temperature, grind , vested powdery component A;

[0055] Take 5g of component A, add 5g of deionized water, stir, and wait until component A is completely dissolved to obtain an aqueous solution;

[0056] Get 15g dehydrated alcohol, add 2g camphor wherein, treat that after camphor dissolves completely, add 1g part of Fructus Cnidii ethanol extract, 0.6g Asarum ethanol extract, 0.8g lavender volatile oil, 0.2g Asarum volatile oil, make each component Completely miscible to obtain ethanol;

[0057] Under the condition of stirring, slowly add the ethanol agent into the aqueous solution, and then add 0.1 g of hyaluronic acid, and mix evenly to obtain the product.

Embodiment 3

[0059] Take 6g of component A prepared in implementation 1, add 6g of deionized water, stir, and wait until component A is completely dissolved to obtain an aqueous solution;

[0060] Get 16g dehydrated alcohol, add 2.5g camphor therein, after camphor dissolves completely, add 1.2g part of Cnidium fruit ethanol extract, 0.2g Asarum ethanol extract, 1g lavender volatile oil, 0.6g Asarum volatile oil, make each group The components are completely miscible to obtain ethanol;

[0061] Under the condition of stirring, slowly add the ethanol agent into the aqueous solution, and then add 0.15 g of hyaluronic acid, and mix evenly to obtain the product.

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Abstract

The invention relates to a skin disinfectant, and in particular relates to a compound skin disinfectant and a preparation method of the compound skin disinfectant. The compound skin disinfectant disclosed by the invention comprises a cnidium, sophora flavescens, coptidis rhizome, Lctuc tiwnin Mxim, honeysuckle, licorice, aqueous extract of comfrey, 1# cnidium, ethanol extract of asarum, lavender, volatile oil of asarum, camphor, hyaluronic acid, anhydrous ethanol and deionized water. The 71-77% medical alcohol serves as a main ingredient and a variety of traditional Chinese medicine germicidal ingredients are added simultaneously and the traditional Chinese medicine germicidal ingredients are in a mutual compatibility to have a synergistic bactericidal effect. The camphor is a macromolecule, and combined with molecules in the traditional Chinese medicine germicidal ingredients under an action of hyaluronic acid after being dissolved in ethanol, so that various components are mixed and dissolved to form a viscous liquid. Most of the traditional Chinese medicine germicidal ingredients retain on the skin surface during a use process to form an antibacterial protection layer.

Description

technical field [0001] The invention relates to a skin disinfectant, in particular to a composite skin disinfectant and a preparation method thereof. Background technique [0002] The skin needs to be disinfected before intravenous injection; currently commonly used skin disinfectants are iodine complex, medical alcohol, etc. Iodine complexes are prone to allergies and pigmentation, and medical alcohol can quickly sterilize the skin, but has no persistent (residual) activity. After the intravenous injection is completed, a needle hole will be left on the skin. Although the needle hole is only a small wound, due to the disappearance of the activity of the previous skin disinfectant, the bacteria in the air are still easy to cause wound infection symptoms such as wound inflammation, and some even persist. Redness and swelling for several days. Contents of the invention [0003] In order to solve the problem that existing skin disinfectants do not have persistent activity, ...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61P31/02A61P17/00A61K31/125
Inventor 张淼刘义庆
Owner SHANDONG PROVINCIAL HOSPITAL
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