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Traditional Chinese medicine composition for curing nephritis of Schonlein-Henoch purpura and preparation method thereof

A technology for purpuric nephritis and a composition, applied in the field of traditional Chinese medicine, can solve problems such as large side effects and disease recurrence, and achieve the effects of improving the cure rate, shortening the course of disease, and having no toxic side effects and drug resistance.

Inactive Publication Date: 2013-04-17
钟山县红花镇中心卫生院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine has not yet formed a unified plan for the treatment of allergic purple fatigue nephritis (hematuria and proteinuria), mainly using glucocorticoids, immunosuppressants and cytotoxic drugs. Although a certain effect has been achieved, the side effects are relatively large and prone to relapse after dose reduction

Method used

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  • Traditional Chinese medicine composition for curing nephritis of Schonlein-Henoch purpura and preparation method thereof
  • Traditional Chinese medicine composition for curing nephritis of Schonlein-Henoch purpura and preparation method thereof
  • Traditional Chinese medicine composition for curing nephritis of Schonlein-Henoch purpura and preparation method thereof

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preparation example Construction

[0087] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is a tablet, specifically:

[0088] In the first step, mix Codonopsis pilosula, Polygonatum, Acanthopanax, Gorgon, Shiwei, Dendrobium, Eclipta, Morinda officinalis and Cistanche in proportion to obtain a mixture, and add an alcohol concentration 1 to 2 times the mass of the mixture. 80%~90% ethanol, stir for 2h~4h, put it into the percolation tank, continue to add ethanol with an alcohol concentration of 80%~90% relative to the mass of the mixture, soak for 24h, percolate, and the percolation liquid The flow rate is 70-85L per hour. At the same time, continuously add ethanol with an alcohol concentration of 80%-90% at this speed. During the percolation process, the ethanol is always kept not lower than the drug surface, and the percolation liquid is collected to be 7-9% of the mass of the mixture. times; ...

Embodiment 1

[0104] The concrete preparation of embodiment 1 syrup 1

[0105] Mix Codonopsis 93g, Polygonatum 51g, Acanthopanax 67g, Gorgon 41g, Shiwei 56g, Dendrobium 60g, Eclipta 98g, Morinda officinalis 69g and Cistanche 65g to obtain a mixture, add 600g of ethanol with an alcohol concentration of 90%, Stir for 4 hours, put into the percolation tank, continue to add 1.8kg of ethanol with an alcohol concentration of 90%, soak for 24 hours, percolate, the flow rate of the percolation liquid is 70L per hour, and continuously add ethanol with an alcohol concentration of 90% at this speed, Keep ethanol not lower than the drug surface during the process of rinsing, collect 5.4kg of percolation liquid, mix 28g of Moutan Cortex, 40g of Arborvitae leaves, 36g of Motherwort, 25g of Digupi, 48g of Schisandra, 18g of Lonicerae vine, 42g of Radix Isatidis, and 25g of Cortex Phellodendri , Mingdangshen 28g, Benzoin 21g, Notopterygium 22g, Poria 37g, Licorice 26g, Achyranthes bidentata 34g, Scrophular...

Embodiment 2

[0106] The concrete preparation of embodiment 2 syrup 2

[0107] Mix Codonopsis 91g, Polygonatum 49g, Acanthopanax 65g, Gorgon 39g, Shiwei 54g, Dendrobium 58g, Eclipta 96g, Morinda officinalis 67g and Cistanche 63g to obtain a mixture, add 600g of ethanol with an alcohol concentration of 80%, Stir for 4 hours, put into the percolation tank, continue to add 1.8kg of ethanol with an alcohol concentration of 80%, soak for 24 hours, percolate, the flow rate of the percolation liquid is 70L per hour, and continuously add ethanol with an alcohol concentration of 80% at this speed, Keep ethanol not lower than the drug surface in the process of rinsing, collect 5kg of percolation liquid, mix 26g of Moutan bark, 38g of oriental cypress leaves, 34g of motherwort, 23g of Digupi, 46g of Schisandra chinensis, 16g of honeysuckle, 40g of Radix Radix, 23g of Phellodendron officinalis, Mingdangshen 26g, Benzoin 19g, Notopterygium 20g, Poria cocos 35g, Licorice 24g, Achyranthes bidentata 32g, S...

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Abstract

The invention provides a traditional Chinese medicine composition for curing nephritis of Schonlein-Henoch purpura. The bulk drugs are as follows: codonopsis pilosula, rhizoma polygonati, acanthopanax, moutan bark, cacumen biotae, leonurus, cortex lycii radicis, schisandra chinensis, honeysuckle stem, isatis roots, cortex phellodendri chinensis, changium smyrnioides, storax, semen euryales, pyrrosia lingua, notopterygium roots, poria cocos, morinda officinalis, liquorice, medicinal cyathula roots, picria fel-terrae, geranium wilfordii, coptis chinensis, dendrobe, eclipta, cistanche, rhizoma atractylodis, roots of fangji and sargentgloryvine stems. The traditional Chinese medicine composition shortens the course of treatment, improves the cure rate and has no toxic and side effect or drug tolerance.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating allergic purpura nephritis and a preparation method thereof. Background technique [0002] Henoch-Schonlein purpura is the most common vasculitic disease in children, characterized by rash, arthralgia, abdominal pain, and glomerular damage. 40% of children with Henoch-Schonlein Purpura develop into purpura nephritis within 4 to 6 weeks after the appearance of typical purpura. The severity of renal injury is the key to determine the long-term prognosis of children with Henoch-Schonlein Purpura. [0003] Allergic purpura nephritis is the renal damage caused by allergic purpura. It is the most common secondary glomerular disease in pediatrics and the main cause of chronic renal failure in children. Primary disease is more common in children and adolescents, more common with 3~14 years old. Most of the cas...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P13/12A61P37/08
Inventor 不公告发明人
Owner 钟山县红花镇中心卫生院
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