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Traditional Chinese medicine composition used for treating coronary heart disease angina

A technology for coronary heart disease angina pectoris and a composition, applied in the field of medicine, can solve the problems of insufficient blood-activating effect, simple prescription, insufficient long-term curative effect, etc., and achieve the effects of improving blood circulation, preventing thrombosis, and reducing myocardial oxygen consumption

Inactive Publication Date: 2013-03-13
山东宏济堂制药集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The medicament has a small amount of medicinal taste, clear active ingredients, and a small dosage, but the prescription of the present invention is simple, and the effect of promoting blood circulation is not obvious enough, so the short-term curative effect is good, and the long-term curative effect is not obvious enough

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The preparation of embodiment 1 tablet

[0047] Prescription: 240g Corydalis corydalis, 8g musk, 8g storax, 120g Chuanxiong, 120g ginseng, 12g borneol.

[0048] Preparation method: (a) add musk and equal amount of starch, mix and grind; storax, add appropriate amount of micro-powdered silica gel, mix and grind; Add 60% ethanol for reflux extraction twice, each time add 6 times the weight of the raw material for ethanol extraction, reflux for 2 hours, combine the extracts, filter, recover the ethanol from the filtrate and concentrate at 60°C to a thick paste with a relative density of 1.30~1.32, add Vinegar-roasted corydalis fine powder and appropriate amount of starch, mixed evenly, granulated, dried, added musk, storax and borneol fine powder, mixed evenly, to obtain the active substance of the drug;

[0049] (b) The pharmaceutical active substance is compressed into 1000 tablets and coated with a film.

Embodiment 2

[0050] The preparation of embodiment 2 capsules

[0051] Prescription: Corydalis corydalis 230g, musk 6g, storax 10g, chuanxiong 130g, ginseng 110g, borneol 15g.

[0052] Preparation method: (a) add musk and equal amount of starch, mix and grind; storax, add appropriate amount of micro-powdered silica gel, mix and grind; Add 60% ethanol for reflux extraction twice, each time add 6 times the weight of the raw material for ethanol extraction, reflux for 2 hours, combine the extracts, filter, recover the ethanol from the filtrate and concentrate at 60°C to a thick paste with a relative density of 1.30~1.32, add Vinegar-roasted corydalis fine powder and appropriate amount of starch, mixed evenly, granulated, dried, added musk, storax and borneol fine powder, mixed evenly, to obtain the active substance of the drug;

[0053] (b) The active substance of the medicine is packed into capsules and made into 1000 capsules.

Embodiment 3

[0054] The preparation of embodiment 3 pills

[0055] Prescription: Corydalis corydalis 250g, musk 10g, storax 6g, chuanxiong 110g, ginseng 130g, borneol 9g.

[0056] Preparation method: (a) add musk and equal amount of starch, mix and grind; storax, add appropriate amount of micro-powdered silica gel, mix and grind; Add 60% ethanol for reflux extraction twice, each time add 6 times the weight of the raw material for ethanol extraction, reflux for 2 hours, combine the extracts, filter, recover the ethanol from the filtrate and concentrate at 60°C to a thick paste with a relative density of 1.30~1.32, add Vinegar-roasted corydalis fine powder and appropriate amount of starch, mixed evenly, granulated, dried, added musk, storax and borneol fine powder, mixed evenly, to obtain the active substance of the drug;

[0057] (b) Pan pills, the active substance of the drug, are made into 1000 pills.

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Abstract

The invention belongs to the technical field of medicines and relates to a traditional Chinese medicine composition used for treating coronary heart disease angina and a preparation method thereof. The traditional Chinese medicine composition used for treating coronary heart disease angina provided by the invention is prepared from the following traditional Chinese medicine composition raw drugs in parts by weight: 220-260 parts of vinegar-processed corydalis tuber, 4-12 parts of musk, 4-12 parts of storax, 100-140 parts of Szechuan lovage rhizome, 100-140 parts of ginseng and 6-18 parts of borneol. The traditional Chinese medicine composition provided by the invention has the efficacies of promoting the circulation of qi and resuscitating, activating blood and dissolving stasis as well as activating meridians to stop pain and is used for treating chest pain, choking sensation in chest, swelling pain at ribs, shortness of breath and palpitation which are caused by Qi-stagnation and blood stasis type coronary heart disease angina.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a traditional Chinese medicine composition for coronary heart disease angina pectoris and a preparation method thereof. Background technique [0002] Coronary heart disease angina pectoris refers to a group of syndromes with precordial pain as the main clinical manifestation caused by coronary artery insufficiency caused by coronary atherosclerotic stenosis, temporary myocardial ischemia and hypoxia. The incidence of coronary heart disease in our country is increasing year by year, seriously endangering the health and life of the people. Coronary heart disease generally includes five types. The most harmful is acute myocardial infarction, which often requires emergency treatment, otherwise the risk is extremely high; the most frequent is angina, including stable and unstable angina, of which stable angina is the most Mild coronary heart disease; also cardiac arrest, painless myoc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61P9/10A61K31/045A61K35/55
Inventor 李樱文哲亮李秀凤高钧
Owner 山东宏济堂制药集团股份有限公司
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