Povidone-iodine disinfectant and preparation method thereof

A technology of povidone-iodine and regulators, which is applied in the direction of disinfectants, botany equipment and methods, antiviral agents, etc., can solve the problems of effect of storage time, increase the concentration of available iodine, promote slow release, and improve the effect the effect of time

Inactive Publication Date: 2013-02-13
QINGDAO VLAND BIOTECH INC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the existing povidone iodine solution disinfectant will affect the effect if it is placed for a long time, and it is analyzed that it is caused by degradation. Ketone iodine solution disinfectant

Method used

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  • Povidone-iodine disinfectant and preparation method thereof
  • Povidone-iodine disinfectant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1, povidone-iodine solution

[0035] Add 100g of povidone-iodine to 200ml of pure water, stir fully at room temperature to dissolve; add 20g of potassium iodide in turn, stir fully at room temperature to dissolve; then add 33g of potassium iodate, stir fully at room temperature to dissolve; add water to 1000ml, and finally Adjust the pH of the solution to 5.0-5.5 with citric acid and sodium hydroxide.

Embodiment 2

[0036] Embodiment 2, povidone-iodine solution

[0037] Add 50g of povidone-iodine to 1000ml of pure water, fully stir at room temperature to dissolve; add 20g of potassium iodide in turn, fully stir at room temperature to dissolve; then add 16.5g of potassium iodate, fully stir at room temperature to dissolve; finally use citric acid and Sodium hydroxide is used to adjust the pH of the solution to 5.0-5.5.

Embodiment 3

[0038] Embodiment 3, povidone-iodine solution

[0039] Add 100g povidone-iodine to 1000ml pure water, stir well at room temperature to dissolve; add 20g potassium iodide in turn, stir well at room temperature to dissolve; then add 12.5g potassium iodate, stir well at room temperature to dissolve; finally use citric acid and Sodium hydroxide is used to adjust the pH of the solution to 5.0-5.5.

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Abstract

The invention discloses a povidone-iodine disinfectant and a preparation method thereof. The povidone-iodine disinfectant comprises povidone-iodine (PVP-I), potassium iodate and potassium iodide. Critic acid and sodium hydroxide are used for adjusting the pH of a solution. The povidone-iodine solution contains potassium iodate and potassium iodide, and under an acid environment, a reaction of IO3<->+5I<->+H<+>=3I2+3H2O exists in the solution. Effective iodine concentration in the solution is increased, active iodine is promoted to be released slowly, and disinfecting time of the povidone-iodine disinfectant is prolonged.

Description

technical field [0001] The invention relates to a process for preparing a disinfectant, in particular to a process for preparing a povidone-iodine solution. Background technique [0002] Povidone-iodine (Polyvinyl pyrrolidone-Iodine, PVP-I), also known as povidone iodine, is a new type of iodine-containing sterilizing preparation. PVP-I is a complex formed by polyvinylpyrrolidone (PVP) and iodine, containing 9 to 12% of available iodine. PVP is a polyethylene non-ionic surfactant with a molecular weight of 10,000-40,000 Da. It has a solubilizing effect and is often used as a drug carrier. PVP is stable in nature and generally does not cause incompatibility with other drugs. After forming a complex with iodine, the iodine element is combined with the inner side of the PVP helical structure, greatly improving the solubility of iodine. At the same time, the product gradually decomposes and the iodine element is released slowly. Play the role of continuous disinfection. PVP i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/12A01P1/00A61K33/18A61K31/79A61P31/04A61P31/12
Inventor 郝智慧冯培生贾德强刘元元王艳玲沈巍
Owner QINGDAO VLAND BIOTECH INC
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