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Capsule shell and preparation method thereof

A technology of capsule shell and capsule shell, which can be used in capsule delivery, pharmaceutical formulations, medical preparations of non-active ingredients, etc. It can solve intestinal irritation and other problems, and achieve the effects of alleviating irritation, improving taste, and inhibiting sugar absorption

Inactive Publication Date: 2012-12-19
SHENGQUAN HEALTANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above methods use plant-derived hydroxypropyl methylcellulose and chitin to replace the gelatin components in the original process, the stimulation of the intestinal tract by the drug itself is not avoided, and the bitterness produced by the capsule shell during swallowing can't avoid

Method used

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  • Capsule shell and preparation method thereof
  • Capsule shell and preparation method thereof
  • Capsule shell and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take 37g of gelatin, 12.5g of water, 50g of L-arabinose, and 0.5g of glycerin, mix them evenly, and heat them to 80°C to form a glue; shape them by dipping in glue, and dry them at 30°C to get the capsule shell, the performance test results of the capsule shell As shown in Table 1.

Embodiment 2

[0023] Take 70g of hydroxymethyl cellulose, 17.5g of water, 1g of L-arabinose, and 11.5g of acetic acid, mix them evenly, and heat them to 90°C to form a glue solution; shape them by dipping in glue, and dry them at 40°C to obtain capsule shells, capsule shells The performance test results are shown in Table 1.

Embodiment 3

[0025] Take 55g of agar, 15g of water, 25g of L-arabinose, and 5g of titanium dioxide, mix them evenly, and heat them to 85°C to form a glue; shape them by dipping in glue, and dry them at 35°C to obtain a capsule shell. The performance test results of the capsule shell are as follows: Table 1 shows.

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PUM

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Abstract

The invention relates to a capsule shell and a preparation method thereof. The capsule shell comprises 1-50wt% of L-arabinose. The capsule shell is conductive to relieving irritation of drugs to intestinal tracts and shortening the drug absorption time.

Description

technical field [0001] The invention relates to a capsule shell, in particular to a capsule shell containing L-arabinose. Background technique [0002] Capsule shell is an egg-shaped hollow shell used to contain solid powder and granules. It has good bioavailability and can dissolve quickly, reliably and safely. It is mainly used in medicine and pharmaceutical industries. Medical capsule shells are mainly used to contain solid medicines, such as self-made powders, health products, pharmaceuticals, etc. Capsule shells are mostly made of gelatin after refined treatment and auxiliary materials such as starch. If some drugs that have a greater stimulating effect on the stomach are put into the capsule shell, since the stomach does not absorb starch, the capsule will carry the drugs into the small intestine and be absorbed directly, avoiding the stimulation of the drugs to the stomach. However, after the capsule shell is dissolved, irritation of the intestinal tract by the drug...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/26A61K9/48
Inventor 唐地源刘顶王恩华
Owner SHENGQUAN HEALTANG
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