AS-OCT-SD (Anterior Segment-Optical Coherence Tomography-Spectrum Domain) imaging system and AS-OCT-SD imaging method based on visibility function regulation

Abstract

The invention discloses an AS-OCT-SD (Anterior Segment-Optical Coherence Tomography-Spectrum Domain) imaging system and an AS-OCT-SD imaging method based on the visibility function regulation. Low coherent light emitted by a broadband light source can respectively enter into a sample arm and a reference arm after being split by an optical fiber coupler, light returned from the sample arm and the reference arm can respectively enter into a detection arm through a circulator, different light paths can be respectively selected by the light through light switches, the light can irradiate in different areas of a grating, and thus the switching between the reference arm position and the maximum sensitivity position corresponding to the reference arm position can be realized; different light spectrum components after the dispersion by the grating can be gathered on different pixels of a CCD (Charge Coupled Device), interference can be generated, and an OCT image of a sample can be reconstructed after an interference spectrum signal is transmitted to a computer; and two OCT images corresponding to two states of the light switches can be split-jointed, and thus an OCT image with double measuring range can be obtained. According to the AS-OCT-SD imaging system and the AS-OCT-SD imaging method, disclosed by the invention, the AS-OCT-SD imaging can be realized under a high sensitivity premise.

Description

technical field [0001] The present invention relates to optical coherence tomography (OCT) technology, in particular to a full anterior segment spectral domain OCT imaging system and method based on visibility function control. Background technique [0002] Optical Coherence Tomography (OCT for short) is a non-invasive medical imaging method based on low-coherence interference. Anterior Segment OCT (AS-OCT for short) can provide non-contact, real-time static and dynamic The clear part of the anterior segment structure image, since 1994 Izatt et al. first used it for cornea and anterior segment imaging, has become an ideal tool for measuring and analyzing the anterior segment tissue and structure, and can help diagnose cornea, sclera, iris, chamber angle It is especially helpful to the diagnosis and research of common eye diseases such as glaucoma and cataract, and is also widely used in the research of regulation and the pathogenesis of presbyopia. [0003] In recent years,...

AI Technical Summary

Problems solved by technology

The imaging depth of spectral domain OCT is usually 3-4 mm, which cannot meet the needs of full anterior segment imaging

In order to achieve rapid tomographic imaging of the entire anterior segment, there are currently three main methods. One is to use a swept-frequency light source with a relatively narrow instantaneous linewidth, which can achieve rapid imaging of the anterior segment, but its axial resolution is generally lower than that of spectral Resolution of Domain System (SD-OCT)

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