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Application of Irosustat in preparing drugs resistant to eimeria tenella

A technology of 1. irosustat and Eimeria, applied in the application field of preparing anti-Eimeria tenella medicines, can solve the problem that the effect of anti-Eimeria tenella cannot be inferred, and there is no Irosustat anti-Eimeria tenella. The role of coccidia, etc.

Active Publication Date: 2014-01-15
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Irosustat has attracted much attention in recent years as a drug with promising application prospects in the treatment of breast cancer, but there is no report that Irosustat has an anti-Eimeria tenella effect, and it is impossible to infer whether it has anti-Eimeria tenacia through the known properties of Irosustat. The role of coccidia

Method used

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  • Application of Irosustat in preparing drugs resistant to eimeria tenella
  • Application of Irosustat in preparing drugs resistant to eimeria tenella
  • Application of Irosustat in preparing drugs resistant to eimeria tenella

Examples

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Effect test

Embodiment 1

[0010] Preparation of Irosustat powder: Mix 3g of Irosustat (content not less than 99%) and 97g of starch. Irosustat was purchased from Medkoo Biotechnology Company, USA, item number: 200550.

[0011] The usage and dosage of the powder: mix the above 100g powder into 100kg feed, and feed according to the daily food intake.

Embodiment 2

[0013] Preparation of Irosustat water-soluble powder: Take 3g Irosustat (content not less than 99%) and 97g glucose and mix well. Irosustat was purchased from Shanghai Ensign Pharmaceutical Technology Co., Ltd., product name: BN 83495, product number: 10426.

[0014] Dosage of water-soluble powder: Dissolve 100g of the above-mentioned powder in 200 liters of water, cut off water for 2 hours before using the medicine, and then feed according to the normal amount of drinking water.

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Abstract

The invention discloses application of Irosustat in preparing drugs resistant to eimeria tenella. Irosustat and acceptable auxiliary materials are prepared into powder to be added into feeds with even mixing, and chicken are fed according to daily feed quantity; or the Irosustat is prepared into Irosustat water soluble powder to be dissolved into water, and the chicken are fed according to daily feed quantity. Animal infection experiments prove that the anticoccidialindex (ACI) of the Irosustat can reach to 185. Therefore, the Irosustat has a good function of resisting the eimeria tenella.

Description

technical field [0001] The invention relates to a new application of Irosusat, in particular to the application of Irosusat in the preparation of anti-Eimeria tenella medicaments. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers the intensive chicken industry production, and the economic loss caused by it is as high as more than 2.5 billion pounds every year. Eimeriaspp ), the most harmful of which is Eimeria tenella ( Eimeria tenella ). Although my country has no accurate statistics on this so far, the most conservative estimate is that the loss should not be less than 2.5 billion RMB. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Irosustat (chemical name: 6-oxo-6,7,8,9,10,11-hexahydrocycloheptano[c]benzopyran...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/37A61P33/02
Inventor 孙铭飞谢明权戚南山吴彩艳吕敏娜廖申权温烈娜
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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