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Application of suramin sodium in preparing anticoccidial drug

A technology for suramin sodium and chicken coccidia, which is applied in the field of suramin sodium to achieve the effect of good resistance to Eimeria tenella

Active Publication Date: 2016-02-10
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no report that suramin sodium has an anti-coccidiosis effect on chickens, and it is impossible to infer whether it has an anti-coccidia effect on chickens through the known properties of suramin sodium

Method used

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  • Application of suramin sodium in preparing anticoccidial drug
  • Application of suramin sodium in preparing anticoccidial drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Preparation of suramin sodium powder: Take 2.5g of suramin sodium (content not less than 99%) and 97.5g of soluble starch and mix well.

[0028] The usage and dosage of the powder: mix the above 100g powder into 100kg feed, and feed according to the daily food intake.

Embodiment 2

[0030] Preparation of suramin sodium water-soluble powder: take 2.5g suramin sodium (content not less than 99%) and 97.5g glucose and mix well.

[0031] Dosage of water-soluble powder: Dissolve 100g of the above-mentioned powder in 100 liters of water, and feed according to the normal amount of drinking water.

Embodiment 3

[0033] Preparation of water-soluble powder of medicinal derivatives of suramin sodium: take 2.5g of medicinal derivatives of sodium suramin (content not less than 99%) and 97.5g of glucose and mix well.

[0034] Dosage of water-soluble powder: Dissolve 100g of the above-mentioned powder in 100 liters of water, and feed according to the normal amount of drinking water.

[0035] In the following, suramin sodium is taken as a representative to illustrate the anti-coccidiosis effect of suramin sodium and its medicinal derivatives in combination with specific experiments.

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Abstract

The invention discloses application of suramin sodium in preparing an anticoccidial drug. The suramin sodium, which is uniformly mixed with acceptable adjuvants, is added to feed, so as to effectively resist the breeding of eimeria tenella in chicken bodies. Compared with a conventional anticoccidial drug dinitolmide premix, the anticoccidial drug is significant in anticoccidial effect. The invention can effectively relieve the problem of serious drug tolerance which is generated due to the use of anticoccidial drugs in current breeding industry; and on the basis, the speed of researching and developing new drugs is accelerated, so that the suramin sodium has an important advantage for the green and healthy development of the breeding industry.

Description

technical field [0001] The invention relates to a new application of suramin sodium, in particular to the application of suramin sodium in the preparation of anti-coccidial medicaments for chickens. Background technique [0002] chicken coccidiosis ( Coccidiosis ) is the most common parasitic protozoan disease in chicken production, which is caused by Eimeria apicomplexa parasitic on the intestinal epithelial cells of chickens. It mainly harms chicks under 3 months of age, and the mortality rate can reach 80%. The chicks that have endured grow slowly and are stunted. Most of the adult chickens are worm-carriers, with slow weight gain and decreased egg production rate. The harm to the chicken industry is very serious, and it causes huge economic losses to the chicken industry every year. Among the seven Eimeria species that have been reported, Eimeria tenella has the strongest pathogenicity and occurs widely. Today, the degree of intensification of the chicken industry is ...

Claims

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Application Information

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IPC IPC(8): A61K31/185A23K50/75A23K20/10A61P33/02
Inventor 吴彩艳孙铭飞李娟廖申权戚南山林栩慧吕敏娜吴丹凤
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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