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Application of cinnamic acid in preparation of drugs for preventing and treating livestock and poultry virus infection

A technology of virus infection and cinnamic acid, which is applied in the field of cinnamic acid, can solve the problems that have not been seen in the application of cinnamic acid, and achieve the effect of improving survival rate and production performance, good effect, and reducing mortality

Active Publication Date: 2012-07-25
承德普润生物制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] At present, there is no application of cinnamic acid in livestock and poultry anti-virus

Method used

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  • Application of cinnamic acid in preparation of drugs for preventing and treating livestock and poultry virus infection
  • Application of cinnamic acid in preparation of drugs for preventing and treating livestock and poultry virus infection
  • Application of cinnamic acid in preparation of drugs for preventing and treating livestock and poultry virus infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: cinnamic acid oral liquid (cinnamic acid concentration is 100mg / ml)

[0035] 1. Composition: 10g of cinnamic acid, 25ml of absolute ethanol, 25ml of Tween-80, and 100ml of water for injection.

[0036] 2. Preparation method: first dissolve cinnamic acid in absolute ethanol, then add Tween 80, and finally add water for injection slowly to make up to 100ml.

Embodiment 2

[0037] Embodiment 2: cinnamic acid oral liquid (cinnamic acid concentration is 90mg / ml)

[0038] 1. Composition: 9 g of cinnamic acid, 20 ml of absolute ethanol, 30 ml of Tween-80, and 100 ml of water for injection.

[0039] 2. Preparation method: first dissolve cinnamic acid in absolute ethanol, then add Tween 80, and finally add water for injection slowly to make up to 100ml.

Embodiment 3

[0040] Embodiment 3: cinnamic acid oral liquid (cinnamic acid concentration is 100mg / ml)

[0041] 1. Composition: 10g of cinnamic acid, 30ml of absolute ethanol, 30ml of Tween-80 solution, and 100ml of water for injection.

[0042] 2. Preparation method: first dissolve cinnamic acid in absolute ethanol, then add Tween 80, and finally add water for injection slowly to make up to 100ml.

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Abstract

The invention relates to application of cinnamic acid in the preparation of drugs for preventing and treating livestock and poultry virus infection. Cinnamic acid has an activity resisting to poultry virus diseases, and can effectively prevent and treat infections of a bird flu H9 subtype virus, a bird flu H5 subtype virus, an infectious bursal disease virus LX strain, a nephropathogenic infectious bronchitis virus and an avian infectious laryngotracheitis virus, so that the death rate of diseased chickens is reduced, the survival rate of the poultry is effectively increased and the parturition performance of the poultry is effectively improved.

Description

technical field [0001] The invention relates to a new application of cinnamic acid, in particular to the application of cinnamic acid in the preparation of medicines for preventing and treating viral infection of livestock and poultry. Background technique [0002] Phenolic acid compounds are widely distributed in medicinal plants, such as ebony in Rosaceae, honeysuckle in Lonicera family, angelica and chuanxiong in Umbelliferae, etc. Various phenolic acids have a wide range of pharmacological activities, such as scavenging free radicals, anti-inflammation, anti-virus, immune regulation, anti-coagulation and anti-tumor effects. At the same time, studies have shown that ferulic acid has a significant inhibitory effect on cold viruses, respiratory syncytial virus and HIV. Professor Eich discovered that chlorogenic acid is a promising lead compound against HIV when he was studying plant metabolites as antiretroviral agents. In the process of studying Geranium sativa, it was f...

Claims

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Application Information

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IPC IPC(8): A61K31/192A61P31/12A61P31/16A61P31/14A61K31/205
Inventor 何诚欧长波潘青
Owner 承德普润生物制药有限公司
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