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Compound cod-liver oil ointment as well as preparation method and application thereof

A technology of cod liver oil and ointment, which is applied in ointment delivery, pharmaceutical formulations, and medical raw materials derived from fish feed, etc. It can solve the problems of poor circulation of blood in the local anal canal and loss of nutrition in wounds, so as to achieve no rancidity and promote epithelial regeneration. Differentiation, no adverse stimulating effect

Active Publication Date: 2014-05-14
BEIJING RECTUM HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, due to anal fissure, perianal redness, perianal ulcer, perianal pain, including perianal wound healing, etc., skin cracks, repeated infection of evil poison, local anal canal blood circulation is not smooth, and the wound loses nutrition. ulcer
For this symptom, the existing medicines can not relieve the pain of skin laceration, nourish the wound, and achieve the effect of healing in a targeted manner.

Method used

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  • Compound cod-liver oil ointment as well as preparation method and application thereof
  • Compound cod-liver oil ointment as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] 1. Prescription: Cod liver oil 100g, zinc oxide 50g, ethacridine lactic acid 5.0g, yellow petrolatum to 1000g, and 1000g ointment.

[0036] 2. Preparation method: Weigh zinc oxide and ethacridine lactate coarse powder raw materials according to this embodiment, crush them, and sieve them for later use; melt yellow vaseline at a temperature of 50°C and add them in proportion to zinc oxide and ethacridine lactate In the mixed fine powder after pulverization of pyridine, in the molten state, adjust the mixer to a rotating speed of 180 for uniform stirring, add cod liver oil during the stirring process, and mix until semi-solidified to obtain.

Embodiment 2

[0038] 1. Prescription: Cod liver oil 100g, zinc oxide 50g, ethacridine lactic acid 5.0g, borneol 0.9g, white petrolatum to 1000g, and 1000g ointment.

[0039] 2. Preparation method: Weigh zinc oxide and ethacridine lactate coarse powder raw materials according to this embodiment, crush them, and sieve them for later use; melt white vaseline at a temperature of 55°C and add them in proportion to zinc oxide and ethacridine lactate In the mixed fine powder after pulverization of pyridine, in the molten state, adjust the mixer speed to 180 for uniform stirring. During the stirring process, add cod liver oil and borneol solution dissolved in ethanol, mix until semi-solidified, and obtain. The ointment effect that makes by present embodiment is the best.

Embodiment 3

[0041] 1. Prescription: 120g cod liver oil, 35g zinc oxide, 6.5g ethacridine lactate, 0.6g borneol, add yellow petrolatum to 1000g, prepare 1000g ointment.

[0042] 2. Preparation method: Weigh zinc oxide and ethacridine lactate coarse powder raw materials according to this embodiment, crush them, and sieve them for later use; melt yellow vaseline at a temperature of 60°C and add them in proportion to zinc oxide and ethacridine lactate In the mixed fine powder after pulverization of pyridine, in the molten state, adjust the mixer speed to 200 for uniform stirring. During the stirring process, add cod liver oil and borneol solution dissolved in acetone, and mix until semi-solidified.

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Abstract

The invention relates to a compound cod-liver oil ointment as well as a preparation method and application thereof. The compound cod-liver oil ointment comprises the following raw materials in parts by weight: 80-120 parts of cod-liver oil, 35-65 parts of zinc oxide and 3.5-6.5 parts of ethacridine lactate. The compound cod-liver oil ointment has the effects of removing necrotic tissue, promoting granulation, converging, diminishing inflammation, reliving itching, clearing heat and reliving pain and promoting wound healing and has obvious curative effects of treating skin mucosa ulcer and sufferings and red swollen crissum. As a whole, the compound cod-liver oil ointment has the advantages that the curative effect is definite, use is convenient, acting is quick and the like, and is safe; no pain is generated; and the effective rate of the compound cod-liver oil ointment reaches 100%.

Description

technical field [0001] The invention relates to a compound ointment, in particular to a compound cod liver oil ointment, its preparation method and application. Background technique [0002] Anal fissure is a prismatic fissure or ulcer formed by the rupture of the anal canal skin below the dentate line. It is mostly caused by constipation, excessive defecation, and rupture of the anal skin. From the perspective of infection, it is mainly the anal crypt infection at the back of the anus, and the inflammation spreads to the subcutaneous part of the anal canal, resulting in the rupture of subcutaneous abscess and anal fissure. Anal fissure can cause perianal redness, perianal ulcer, perianal pain and other perianal diseases. [0003] At present, ointments for the treatment of the above-mentioned perianal diseases, including perianal wound healing, are not uncommon in China. There are traditional Chinese medicine prescriptions and western medicine prescriptions. However, due t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K35/60A61K33/30A61P1/00A61P17/02A61P29/00A61P17/04A61K31/59A61K31/07A61K31/473
Inventor 白蕊卢克捷何金哲谭静范朱钢孙冰
Owner BEIJING RECTUM HOSPITAL
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