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Coating material for complex tablets and preparation method thereof

A technology for compound Danshen tablets and coating materials is applied in the directions of plant raw materials, medical preparations with inactive ingredients, medical preparations containing active ingredients, etc. To solve the problem of film coating, prevent the precipitation of borneol, and have good moisture-proof performance

Active Publication Date: 2012-07-04
ZHENGZHOU RUILONG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the existing film coating materials, it is difficult to ensure that the drug does not absorb moisture and the borneol does not precipitate

Method used

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  • Coating material for complex tablets and preparation method thereof
  • Coating material for complex tablets and preparation method thereof
  • Coating material for complex tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The coating material for Compound Danshen Tablets of the present embodiment is made up of the following raw materials in parts by weight: 3 parts of acrylic resin No. VI solution with a concentration of 30%, 12 parts of red iron oxide suspension with a concentration of 30%, 1 part of glycerin 1 part, 1 part of talcum powder, 60 parts of purified water.

[0016] The preparation method of the coating material for compound Danshen tablets of the present embodiment comprises the following steps, taking parts by weight as 3 parts of acrylic resin solution, 12 parts of red iron oxide suspension and 1 part of glycerin, 1 part of talcum powder Mix evenly with 60 parts of purified water, stir for 25 minutes, and make a uniform film coating liquid material. The concentration of the acrylic resin solution is 30%; the concentration of the red iron oxide suspension is 30%.

Embodiment 2

[0018] The coating material for the compound Danshen tablet of the present embodiment is made up of the following raw materials in parts by weight: 5 parts of acrylic resin solution with a concentration of 30%, 15 parts of red iron oxide suspension with a concentration of 30%, 3 parts of glycerin, 3 parts of talcum powder, 70 parts of purified water.

[0019] The preparation method of the coating material for compound Danshen tablets of the present embodiment comprises the following steps, taking parts by weight of acrylic resin solution of 5 parts, 15 parts of red iron oxide suspension and 3 parts of glycerin, 3 parts of talcum powder Mix evenly with 70 parts of purified water, stir for 30 minutes, and make a uniform film coating liquid material. The concentration of the acrylic resin solution is 30%; the concentration of the red iron oxide suspension is 30%.

Embodiment 3

[0021] The coating material for the compound Danshen tablet of the present embodiment is made up of the following raw materials in parts by weight: 8 parts of acrylic resin solution with a concentration of 30%, 20 parts of red iron oxide suspension with a concentration of 30%, 5 parts of glycerin, 5 parts of talcum powder, 80 parts of purified water.

[0022] The preparation method of the coating material for compound Danshen tablets of the present embodiment comprises the following steps, taking parts by weight of acrylic resin solution of 8 parts, 20 parts of red iron oxide suspension and 5 parts of glycerin, 5 parts of talcum powder Mix evenly with 80 parts of purified water, and stir for 35 minutes to make a uniform film coating liquid material. The concentration of the acrylic resin solution is 30%; the concentration of the red iron oxide suspension is 30%.

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Abstract

The invention relates to a coating material for complex tablets and a preparation method thereof. The coating material is composed of following raw materials by weight: 3 parts to 8 parts of acrylic resin solution, 12 parts to 20 parts of red iron oxide injectable suspension, 1 part to 5 parts of glycerol, 1 part to 5 parts of talcum powder and 60 parts to 80 parts of purified water. The complex tablet thin membrane coated tablet made of the coating material is even in tablet surface color and strong in coating membrane adhesion. Accelerated tests and long term experiments show that the coating material is good in humidity resistance, can effectively prevent volatile element borneol from sublimating and dissolving out, and guarantees quality stability of products in an efficacy period.

Description

technical field [0001] The invention relates to a coating material for compound salvia miltiorrhiza tablets, and also relates to a preparation method of the coating material, which belongs to the technical field of medicine preparation. Background technique [0002] Compound Danshen Tablets are composed of Danshen, Panax notoginseng and Borneol. The product contains Danshen extract and Borneol. Among them, the amount of Danshen extract is relatively large, plain tablets are easy to absorb moisture, and Borneol has a certain volatility, which can only be obtained by coating. Effectively prevent tablet moisture absorption and borneol precipitation. Sugar coating is commonly used. In recent years, film coating has been widely used as one of the major achievements in the development of preparation technology. The existing film coating materials are difficult to ensure that the medicine does not absorb moisture and the borneol does not separate out. Contents of the invention ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/32A61K47/10A61K47/04A61K9/32A61K36/537
Inventor 王洪涛付战胜屈荣华孟昭军陈华瑞陈一宁崔凌君
Owner ZHENGZHOU RUILONG PHARMA
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