Meloxicam tablets for dogs and cats and preparation method for meloxicam tablets

Abstract

The invention relates to the field of medicine, and discloses meloxicam tablets for dogs and cats and a preparation method for the meloxicam tablets. The preparation method mainly comprises: a mixing step, a granulation step, a drying step, a granulation straightening step, a granule mixing step and a tabletting step. The meloxicam tablets consist of the following components in percentage by mass: 0.1 to 0.6 percent of meloxicam, 50 to 70 percent of lactose, 20 to 40 percent of microcrystalline cellulose, 3 to 5 percent of hydroxypropyl cellulose, 0.4 to 0.6 percent of sodium citrate, 1 to 5 percent of cross-linked polyvinylpyrrolidone, 4 to 8 percent of polyvinylpyrrolidone (PVP) K30, 0.2 to 0.8 percent of aspartame and 0.60 to 2 percent of magnesium stearate. The meloxicam tablets have small irritation on the intestines and stomach of the dogs and the cats, and are favorable for the absorption of active ingredients.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a meloxicam tablet for dogs and cats and a preparation method thereof. Background technique [0002] Osteoarthritis is a degenerative bone and joint disease in dogs, and it is also a relatively common and frequent disease in dogs. Among dogs over 1 year old, almost one out of every 5 dogs suffers from osteoarthritis of varying degrees, and the incidence increases with age, about 95% of the cases occur in dogs over 5 years old, 50 % Occurs in senior dogs over 10 years of age. Osteoarthritis can occur in dogs of all ages and breeds, and in all joints. Almost half of the cases occur in large dogs, such as German Shepherds, Rottweilers, Labradors, and Golden Retrievers, but they also often occur in smaller Shetland Sheepdogs, Chihuahuas, etc. In recent years, the incidence of canine osteoarthritis has been increasing, which has attracted the attention of veterinary circles all over the wor...

AI Technical Summary

Problems solved by technology

The price of imported drugs is relatively high, which is difficult for many dog ​​and cat owners to accept

In addition, the absorption rate of oral suspension is not high, and the bioavailability is low; while the injection is highly irritating to the local area, which can easily cause pain in dogs and cats, and dogs and cats are more sensitive

However, it is illegal to transfer the human preparations to dogs and cats, and the second is that the dosage is difficult to control, which is prone to medical accidents.

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