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Efficiency connection analysis method fused with structural connection for each brain area

A technology of structural connection and efficacy, applied in the field of analysis and research of brain activity, can solve problems such as lack of fusion, and achieve reliable results.

Inactive Publication Date: 2012-06-20
SOUTHEAST UNIV
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Problems solved by technology

Although this method uses and analyzes the relationship between the two, it still fails to truly integrate the two.

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  • Efficiency connection analysis method fused with structural connection for each brain area
  • Efficiency connection analysis method fused with structural connection for each brain area
  • Efficiency connection analysis method fused with structural connection for each brain area

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Embodiment Construction

[0025] Now in conjunction with accompanying drawing, the present invention will be further described:

[0026] Whole flow process of the present invention can refer to appendix figure 1 , the specific implementation steps are as follows:

[0027] 1. Establishment of brain structural connection network and preprocessing and source reconstruction of magnetic brain signals

[0028] The generation of a high-precision structural connection network from MRI diffusion image DTI to the whole brain requires the following steps: (1) Diffusion-weighted image processing, such as eddy current correction, head motion correction, diffusion tensor model fitting, diffusion tensor (2) Segmentation of gray and white matter; (3) Tracing imaging of white matter nerve fiber tracts; (4) Segmentation of cerebral cortex structures and selection of regions of interest; ( 5) Extract the backbone network according to the region of interest that needs to be analyzed, and convert it into a graph. Each ...

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Abstract

The invention discloses an efficiency connection analysis method fused with structural connection for each brain area. The method comprises the following steps of: extracting and analyzing a brain structural network of an interested area, and converting obtained structural information into a prior probability distribution space of an efficiency connection parameter; establishing an efficiency connection model based on a variational Bayesian framework; and evaluating efficiency connection of each brain area through ensemble learning and an EM (Expectation Maximization) algorithm. Compared with other methods, the method has the advantages that: 1, structural connection is mapped to the prior probability space of the efficiency connection parameter, and a model parameter is optimized in subsequent ensemble learning, so that a relation between the structural connection and the efficiency connection is reflected truly; and 2, structural connection information is combined, so that a result of brain activity analysis is more reliable, and convenience is brought to the discuss of the practical situation of an individual.

Description

technical field [0001] The invention relates to a calculation method of performance connection of fusion structure connection, which belongs to the fields of medical image methodology and medical image signal processing, and is applicable to the analysis and research of brain activity. Background technique [0002] Previous studies have found that mental illnesses including depression, schizophrenia, and epilepsy are all related to structural or functional impairments of the brain. The structural information (structural connectivity) and functional information (functional connectivity, functional connectivity) of the brain reflect the condition of the whole brain, and play an important role in the exploration and research of the pathological mechanisms of various mental diseases. Moreover, there is a close relationship between structural connectivity and functional (functional) functional connectivity. Functional (effective) functional connectivity reflects structural connec...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/00G06F19/00A61B5/055
Inventor 卢青姚志剑罗国平
Owner SOUTHEAST UNIV
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