Method for preparing bupleurum and cassia twig freeze-dried oral preparation

A technology for oral preparations and cassia twigs, which is used in freeze-dried delivery, antiviral agents, pharmaceutical formulations, etc., can solve the problems of inconvenient carrying of decoctions, inappropriate preparation in large quantities, and inability to store for a long time, and achieves fast onset, convenient administration, The effect of low bacterial content

Inactive Publication Date: 2012-06-13
哈药集团中药二厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the problems of inconvenient portability, unfavorable large-scale preparation and long-term storage of the decoction prepared by the traditional cooking method of the existing "Bupleurum cinnamon twig decoction", and to provide a preparation of a freeze-dried oral preparation of Bupleurum cinnamon twigs method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0021] Specific embodiment 1: The preparation method of a kind of Bupleurum cinnamon twig freeze-dried oral preparation of this embodiment is carried out according to the following steps: 1. Weigh 20-35 parts of Bupleurum radix, 9-15 parts of cassia twig, 9 parts of ginseng ~15 parts, 9~15 parts of Scutellaria baicalensis, 9~15 parts of white peony root, 15~20 parts of Pinellia chinensis, 5~10 parts of roasted licorice, 9~15 parts of ginger, 9~15 parts of jujube; Add water to decoct twice, the amount of water added for the first time is 10 to 12 times the weight of the total medicinal materials weighed in step 1, after soaking for 1 hour, decoct for 1 to 1.5 hours, filter, and the decoction is used for later use; The amount of water is 10 to 12 times the weight of the total medicinal materials weighed in step 1, decocted for 1 to 1.5 hours, filtered, and combined twice; Clear paste with a density of 1.06-1.16; 4. Centrifuge the clear paste obtained in step 3, and concentrate t...

specific Embodiment approach 2

[0024] Specific embodiment 2: The difference between this embodiment and specific embodiment 1 is that in step 1, 25 to 30 parts of Bupleurum bupleuri, 10 to 13 parts of cassia twig, 10 to 13 parts of ginseng, and 10 to 30 parts of scutellaria baicalensis are weighed in step 1. 13 parts, 10-13 parts of white peony, 16-19 parts of Pinellia chinensis, 6-9 parts of roasted licorice, 10-13 parts of ginger, and 10-13 parts of jujube. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0025] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is: in step 2, the amount of water added for the first time is 10.5 to 11.5 times of the total amount of medicinal materials, decocting for 1.1 to 1.3 hours; the amount of water added for the second time is 10.5 to 11.5 times the amount of the total medicinal materials, decocting for 1.1 to 1.3 hours. Others are the same as in the first or second embodiment.

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Abstract

The invention discloses a method for preparing a bupleurum and cassia twig freeze-dried oral preparation, relates to a method for preparing a freeze-dried oral preparation, and aims to solve the problems that decoction decocted by the traditional decoction method for the conventional bupleurum and cassia twig decoction is inconvenient to carry and unsuitable to be massively prepared and cannot be stored for a long time. The method for preparing the bupleurum and cassia twig freeze-dried oral preparation comprises the following steps of: 1, weighing raw materials; 2, decocting in water, and extracting decoction; 3, concentrating the decoction; 4, centrifuging, and concentrating again; and 5, performing vacuum freeze-drying to prepare the bupleurum and cassia twig freeze-dried oral preparation. The product has the advantages of definite curative effect, quick response and high stability, is convenient to carry and take, and has the shelf life of 2 years, and the total effective rate is 98.6 percent through the clinical analysis of 2,650 influenza cases. The method is used for preparing the freeze-dried oral preparation.

Description

technical field [0001] The invention relates to a preparation method of a freeze-dried oral preparation. Background technique [0002] Flu is one of common human diseases, with headache, nasal congestion, runny nose, sneezing, aversion to wind and cold, heating, floating pulse, etc. as the main clinical manifestations. Among them, the influenza epidemic can be traced back to a long time ago. It is an acute viral respiratory infectious disease that seriously endangers human health and has become a widespread epidemic in most countries in the world. Influenza is prone to periodic pandemics or worldwide epidemics, bringing serious disasters to mankind. The loss caused by influenza cannot be ignored. According to the report of the American Science and Technology Committee, the number of people who die from influenza in the United States with advanced technology in recent years is 20,000 to 40,000 each year. Influenza has become a viral infectious disease with a high fatality ra...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/19A61P25/08A61P31/14A61P31/16
Inventor 秦绪江赛春梅刘文亮吕晓霞曲林凌雪宇李殿明王英新
Owner 哈药集团中药二厂
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