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Method for preparing pharmaceutical composition for treating functional uterine bleeding

A uterine bleeding, functional technology, applied in the direction of drug combination, pharmaceutical formula, disease, etc., can solve the pain of patients and other problems

Active Publication Date: 2013-10-23
ZHUZHOU QIANJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Regarding the treatment of anovulatory DUB, Western medicine mainly uses hormone therapy and hemostatic drugs. If the effect is not good, further surgery and curettage or even hysterectomy can be taken, which will cause great pain to the patient.

Method used

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  • Method for preparing pharmaceutical composition for treating functional uterine bleeding
  • Method for preparing pharmaceutical composition for treating functional uterine bleeding
  • Method for preparing pharmaceutical composition for treating functional uterine bleeding

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Take 1000g of Radix Paeoniae Rubra, 300g of Panax notoginseng, 1000g of Motherwort, and 1000g of Agrimony, and grind them into coarse powder, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time for 2 hours, the second time for 1 hour, combine the extracts, and filter , the filtrate decompresses and recovers ethanol to a clear paste with a relative density of 1.08 (60°C), centrifuges (3000 rpm, 5 minutes), and concentrates to a thick paste with a relative density of 1.18 (60°C), for subsequent use; take Burnet Add 600g of charcoal and 600g of Puhuang charcoal to decoct twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoction with water, filter, and concentrate the filtrate to a thick paste with a relative density of 1.18 (60°C). Add ethanol to make the ethanol content reach 70%, let it stand for 24 hours, take the supernatant to recover ethanol, and concentrate to a thick paste with a relative density of 1.1...

Embodiment 2

[0021] Take 900g of Radix Paeoniae Rubra, 200g of Panax notoginseng, 1100g of Motherwort, and 1100g of Agrimony, and grind them into coarse powder, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time for 2 hours, the second time for 1 hour, combine the extracts, and filter , the filtrate decompresses and recovers ethanol to a clear paste with a relative density of 1.05 (60°C), centrifuges (3000 rpm, 5 minutes), and concentrates to a thick paste with a relative density of 1.20 (60°C), for subsequent use; take Burnet Add 700g of charcoal and 700g of Puhuang charcoal to decoct twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoction with water, filter, and concentrate the filtrate to a thick paste with a relative density of 1.20 (60°C). Add ethanol to make the ethanol content reach 70%, let it stand for 24 hours, take the supernatant to recover ethanol, and concentrate it to a thick paste with a relative density of 1...

Embodiment 3

[0023] Take 1100g of Radix Paeoniae Rubra and 400g of Panax notoginseng, grind them into coarse powder, add 6 times the amount of 80% ethanol to reflux and extract twice, the first time for 2 hours, and the second time for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate under reduced pressure. The clear paste with a relative density of 1.10 (60°C), centrifuged (3000 rpm, 5 minutes), and concentrated to a thick paste with a relative density of 1.15 (60°C), set aside; take 900g of Motherwort, 900g of Agrimony, Burnet Add 500g of charcoal and 500g of Puhuang charcoal to decoct twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoction with water, filter, and concentrate the filtrate to a thick paste with a relative density of 1.15 (60°C). Add ethanol to make the ethanol content reach 70%, let it stand for 24 hours, take the supernatant to recover ethanol, and concentrate it to a thick paste with a relative density of...

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Abstract

The invention provides a method for preparing a pharmaceutical composition for treating functional uterine bleeding. Root of common peony, pseudo-ginseng, motherwort and hairyvein agrimony are crushed into coarse powder and prepared into a pharmaceutical thick paste A through an ethanol extraction method; coked great burnet and coked cattail pollen are decocted with water to obtain a pharmaceutical thick paste B; the two pharmaceutical thick pastes are combined to obtain the pharmaceutical composition. The pharmaceutical composition of the invention has efficacies of removing stasis, stopping bleeding, regulating menstruation and nourishing blood, can effectively treat functional uterine bleeding and generates no untoward reaction.

Description

technical field [0001] The invention relates to a method for preparing a traditional Chinese medicine composition, in particular to a method for preparing a pharmaceutical composition that can be used for treating functional uterine bleeding. Background technique [0002] Metrorrhagia refers to the menstrual cycle, menstrual period, and menstrual flow are seriously disordered, and the menstrual blood is violently or continuously dripping. It is a frequently-occurring and intractable disease in gynecology. According to some statistics, patients with metrorrhagia account for about 1 / 3 of gynecological outpatient clinics. This disease is equivalent to functional uterine bleeding in Western medicine, and is particularly similar to anovulatory DUB. [0003] Dysfunctional uterine bleeding is abnormal uterine bleeding caused by dysfunction of the neuroendocrine system, referred to as "gong blood", which is one of the common diseases in obstetrics and gynecology. According to sta...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61P15/00
Inventor 刘建武朱大安王振勇
Owner ZHUZHOU QIANJIN PHARMA
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