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Novel natural herbal compound composition with sobering and liver protection effects and application thereof

A composition and technology of sobering up, applied in the direction of medical preparations containing active ingredients, drug combinations, active ingredients of heterocyclic compounds, etc., can solve the problems of failing to meet the requirements of fast and efficient treatment, and achieve the effect of sobering up and protecting viscera Significant, low-cost, good synergistic effect

Inactive Publication Date: 2012-04-18
中哈福生物医药科技(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the role or effect of these material components alone is far from meeting the requirements of fast and efficient treatment.

Method used

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  • Novel natural herbal compound composition with sobering and liver protection effects and application thereof
  • Novel natural herbal compound composition with sobering and liver protection effects and application thereof
  • Novel natural herbal compound composition with sobering and liver protection effects and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] A composition with functions of sobering up and protecting the liver, the active ingredients of which are: 5.98% sesamin, 0.20% schisandrin B, 29.9% Hovenia dulcis fruit extract, 29.9% kudzu flower extract, 29.9% Cyperus cyperus extract %, vitamin E acetate 3.99% and vitamin B120.0002%.

[0056] The preparation method of the composition is as follows: according to the ratio of the above-mentioned active ingredients, take corresponding amounts of raw material sesamin, raw material Schisandra B, raw material Hovenia dulcis extract, raw material kudzu flower extract, raw material Cyperus extract, The raw materials vitamin E acetate and vitamin B12 are mixed evenly, and the product is ready.

[0057] Below to above-mentioned composition (hereinafter referred to as compound), from acute toxicity experiment, to the preventive efficacy (mouse compound recipe low, middle, high dose) of acute alcoholism, to the therapeutic effect of acute alcoholism (mouse compound recipe low, m...

Embodiment 2～8

[0118] Examples 2-8 are compositions with the same ingredients but different contents. The compositions and contents of their corresponding active ingredients are shown in Table 3. Experiments have proved that the compositions of Examples 2-8 also have significant functions of sobering up and protecting the liver.

[0119] The composition of table 3 embodiment 2~8

[0120]

[0121] According to the present invention, when using the composition of the present invention for human health care or adjuvant treatment, the dosage shown in Table 4 is recommended.

[0122] Table 4

[0123]

[0124]

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PUM

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Abstract

The invention discloses a novel natural herbal compound composition with sobering and liver protecting effects and preparation as well as application thereof. The composition is prepared from active ingredients which mainly have the sobering and liver protecting effects and auxiliary materials, wherein the composition of the active ingredients comprise the following components in percentage by weight based on total weight of the active ingredients: 3-10 percent of sesamin, 0.05-5 percent of schisandrin, 10-45 percent of hovenia dulcis thumb extract, 10-45 percent of kudzu vine flower extract, 10-45 percent of nutgrass galingale rhizome extract, 0-0.02 percent of vitamin B12 and 1-10 percent of vitamin E acetate. The invention also relates to application of the composition to preparation of health care foods for preventing and / or treating acute alcoholism, health care foods for treating chronic alcoholic liver damage and health care foods for treating nonalcoholic fatty liver. The composition has the advantages of good synergistic reaction among the components, obvious curative effect, readily available raw materials, easiness in preparation and relatively low cost.

Description

technical field [0001] The invention relates to a composition having the effect of sobering up and protecting the liver, containing various natural herbal plant extracts and its application as a sobering up and protecting the liver health food. Background technique [0002] Alcoholism has become a worldwide public health problem. Excessive alcoholism often leads to acute alcoholism, while long-term, heavy drinking of alcoholic beverages can lead to liver damage, which is alcoholic liver disease (ALD) . The early stage of alcoholic liver disease often manifests as fatty liver. If it is not treated effectively, it will further develop into alcoholic hepatitis, alcoholic liver fibrosis and alcoholic liver cirrhosis. At present, there are many health foods for the prevention and treatment of fatty liver. For example, lipid-lowering health foods include clofibrate, niacin, etc.; liver-protecting and fat-removing health foods include unsaturated fatty acids and phospholipids. He...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P39/02A61P1/16A23L1/302A61K31/355A61K31/36A61K31/714A23L33/15
Inventor 周玉付王美好
Owner 中哈福生物医药科技(上海)有限公司
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