Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Valnemulin hydrochloride granule and preparation method thereof

A technology of warnemulin hydrochloride and granules, which is applied in the field of warnemulin hydrochloride granules and its preparation, can solve the problems of unstable odor and other problems, and achieve the effects of good taste, fast absorption and rapid effect

Inactive Publication Date: 2012-04-11
上海恒丰强生物技术有限公司
View PDF1 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] An object of the present invention is to provide warnemulin hydrochloride granules, so as to overcome the shortcomings of existing warnemulin hydrochloride premixes such as very large peculiar smell and instability

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The warnemulin hydrochloride granules are made of warnemulin hydrochloride as the main ingredient and appropriate amount of filler and wetting agent by weight percentage.

[0024] formula:

[0025] Warnemulin Hydrochloride 10%

[0026] Round porous sucrose pellets 1%

[0027] Distilled water 89%.

[0028] production method

[0029] Dissolving the warnemulin hydrochloride with distilled water first, then adding round porous sucrose pellets and stirring until uniformly mixed to obtain the warnemulin hydrochloride granules.

[0030] Because warnemulin hydrochloride itself has great peculiar smell and instability, the present invention makes it into granules to overcome the peculiar smell of warnemulin hydrochloride and increase its stability. Dosage form, the present invention increases the dosage form of the same medicine, makes administration more diverse, and satisfies the deficiency of the market. The warnemulin hydrochloride granule of the present invention has t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a valnemulin hydrochloride granule which comprises the following raw materials by weight: 10% of valnemulin hydrochloride, 89% of fillers, and 1% of wetting agents. The invention also discloses a preparation method of the valnemulin hydrochloride granule. Since valnemulin hydrochloride itself has heavy peculiar smell and is unstable, the invention prepares granules to overcome the peculiar smell of valnemulin hydrochloride, and improves the stability; no dosage form administrated in a granule form is on the market; the invention introduces a dosage form of a same medicament, makes the administration become more diverse, and meets the deficiency in the market. The valnemulin hydrochloride granule of the invention has the advantages of fast absorption, quick effect, capability of overcoming the deficiencies of former dosage forms, convenience, stability, and good taste.

Description

technical field [0001] The invention belongs to the field of veterinary drug antibiotics, in particular to warnemulin hydrochloride granules and a preparation method thereof. Background technique [0002] Valnemulin hydrochloride (also known as fluvonimulin, Valnemulin), the chemical name is ((2-((R)-2-amino-3-methylbutyrylamino)-1,1-dimethylethyl group) mercapto) acetic acid, (3aS, 4R, 5S, 6S, 8R, 9R, 9aR, 10R)-octahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl - 3a,9-Propane-3aH-cyclopentacyclooctene-1(4H)-one-8-ester. Vernimulin is a new generation of pleuromutilin semi-synthetic antibiotics. It belongs to the diterpene class and belongs to the same class of drugs as tiamulin. It is a special antibiotic for animals. It is mainly used to prevent mycoplasma disease and Gram-positive bacterial infection in pigs, cattle, sheep and poultry. In 1999, it was approved by the European Community for the prevention and treatment of swine dysentery caused by Brachyspira hyodysen...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/16A61K31/22A61P31/04
Inventor 龙谭廖洪
Owner 上海恒丰强生物技术有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com