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Kidney-tonifying spleen-nourishing traditional Chinese medicine formula for treating chronic hepatitis B and chronic hepatitis B virus carriers

A technology for chronic hepatitis B and chronic hepatitis B, which is applied in the direction of pharmaceutical formulas, antiviral agents, medical preparations containing active ingredients, etc., can solve the problems of poor curative effect of virus carriers, and achieve the effect of preventing disease progression and inhibiting replication

Inactive Publication Date: 2012-02-01
SHENZHEN TRADITIONAL CHINESE MEDICINE HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In short, my country is a high-incidence area of ​​HBV. The current hepatitis B vaccine program immunization, the proportion of adults with chronic HBV infection is gradually increasing; high viral load and ALT baseline level, age over 30 years old are independent risks of liver cirrhosis and liver cancer in hepatitis B carriers Factors, the current modern medical antiviral treatment has poor curative effect on chronic hepatitis B and chronic hepatitis B virus carriers, and traditional Chinese medicine has accumulated certain advantages in long-term clinical practice

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Bitter Phalaenopsis 10g, Cuscuta 5g, Lingpi 10g, Eucommia 10g, Achyranthes bidentata 10g, Lycium barbarum 10g, Astragalus 10g, Atractylodes macrocephala 10g, Poria cocos 10g, Polyporus 5g, Fructus aurantii 10g, Salvia miltiorrhiza 10g, Panax notoginseng 3g And turmeric 10g.

Embodiment 2

[0020] Bitter Phalaenopsis 30g, Dodder 10g, Lingpi 30g, Eucommia 15g, Achyranthes bidentata 10~20g, Lycium barbarum 10~20g, Astragalus 20g, Atractylodes macrocephala 15g, Poria cocos 15g, Polyporus 10g, Citrus aurantium 15g, Salvia miltiorrhiza 15g, Panax notoginseng 5g and turmeric 15g.

Embodiment 3

[0022] Bitter Phyllanthus 50g, Dodder 30g, Lingpi 50g, Eucommia 30g, Achyranthes bidentata 30g, Lycium barbarum 30g, Astragalus 40g, Atractylodes macrocephala 30g, Poria cocos 30g, Polyporus 30g, Fructus aurantium 20g, Salvia miltiorrhiza 30g, Panax notoginseng 20g and Turmeric 20g.

[0023] Case selection: 300 cases of chronic hepatitis B patients aged 7 to 65 years old were selected, and a treatment group and a control group were set up; the interactive language response system IVRS was used for randomized management.

[0024] Dosage and usage of the Chinese medicine composition: 1 packet per day, divided into 2 doses, course of treatment: 48 weeks.

[0025] Main efficacy indicators: (1) Serum HBV-DNA was detected at 12, 24, 36, and 48 weeks after taking the drug, and the method was COBAS method; (2) Serum hepatitis B virus markers (HBsAg, HBsAg, HBeAg), using the ARCHITECT i2000SR.

[0026] Below by clinical observation test, further set forth the beneficial effect of inv...

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PUM

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Abstract

The invention relates to a kidney-tonifying spleen-nourishing traditional Chinese medicine formula for treating chronic hepatitis B (including chronic hepatitis B virus carriers), and particularly relates to a traditional Chinese medicine formula which integrates clearing, activating and tonifying and achieves the purpose of treating chronic hepatitis B (including chronic hepatitis B virus carriers) through tonifying kidneys. The traditional Chinese medicine formula is prepared from the following traditional Chinese medicines in parts by weight: 10-50g of phyllanthus amatusniruri, 10-30g of dodder, 10-50g of epimedium, 5-30g of eucommia, 5-30g of achyranthes bidentata, 5-30g of medlar, 10-40g of astragalus root, 5-30g of atractylodes macrocephala, 10-30g of poria, 10-30g of fungus umbellatus, 5-20g of bitter orange, 10-30g of radix salviae miltiorrhizae, 5-20g of panax pseudo-ginseng, 5-20g of radix curcumae. The traditional Chinese medicine formula has the effects of nourishing spleen and tonifying kidneys, clearing away heat and toxic substances as well as nourishing qi and activating blood, and can effectively inhibit the duplication of hepatitis B virus deoxyribonucleic acid (HBV-DNA), reduce the expression of serum hepatitis B virus marks (HBsAG and HBeAG), adjust immune tolerance state through adjusting the organism immune function, and effectively prevent and treat chronic hepatitis B (including chronic hepatitis B virus carriers).

Description

technical field [0001] The invention relates to a traditional Chinese medicine formula for invigorating the kidney and invigorating the spleen for treating chronic hepatitis B and chronic hepatitis B virus carriers, in particular to a Chinese medicinal formula combining clearing, invigorating and nourishing, and treating chronic hepatitis B and chronic hepatitis B virus by invigorating the kidney and invigorating the spleen A traditional Chinese medicine formula for invigorating the kidney and invigorating the spleen of a carrier belongs to the technical field of traditional Chinese medicines. Background technique [0002] Chronic hepatitis B is currently a clinically intractable disease that can gradually evolve into liver cirrhosis, liver cancer, and end-stage liver disease as the disease progresses. Chronic hepatitis B belongs to the categories of "liver pain", "hypochondriac pain" and "accumulation" in the traditional medicine of the motherland. Its disease location is m...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16A61P31/20A61P1/14A61P13/12
Inventor 童光东周大乔
Owner SHENZHEN TRADITIONAL CHINESE MEDICINE HOSPITAL
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