Preparation method for granular Chinese herbal pieces

A traditional Chinese medicine decoction piece and granule type technology, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and bulk transportation, etc. Active ingredient and therapeutic effect, avoidance of volatile ingredient loss, effect of shortening drying time

Inactive Publication Date: 2011-11-02
广州市药材公司中药饮片厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] (1) Traditional Chinese medicine decoction pieces have obvious regional differences in traditional usage habits, the processing methods of decoction pieces in different regions are different, the standards of decoction pieces are not uniform, and the specifications of decoction pieces are inconsistent
Due to the irregular processing of some decoction pieces, thick and large decoction pieces, the dissolution rate of the active ingredients of the medicine will be low when decocting, and the utilization rate of the medicinal materials will be low, which seriously affects the curative effect of traditional Chinese medicine.
[0004] (2) The existing mode of use of decoction pieces mostly adopts the method of pre-prescription weighing and blending, and large-package decoction pieces are usually sold after unpacking. Since the decoction pieces do not have the smallest packaging for independent sales, customers cannot understand the production source of the decoction pieces at all. There is still a lack of strict quality control standards in market monitoring, which provides opportunities for counterfeiting to many small workshop-style processing plants without production licenses for Chinese herbal medicines. The chaos abounds, affecting the clinical efficacy of traditional Chinese medicine and the drug safety of the people
[0005] (3) Most of the traditional Chinese medicine decoction pieces have not been effectively sterilized, and are prone to deterioration such as insects, mildew, oily, discolored, etc., which seriously affect the clinical efficacy of traditional Chinese medicine and the drug safety of the people.
Although granular decoction pieces are beneficial to the dissolution of medicinal ingredients and reduce the dosage of medicinal materials, medicinal materials containing more starch are easy to gelatinize when decocting, which will cause the medicinal liquid to be cloudy and difficult to filter

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1: the preparation method of granular talc Chinese herbal decoction pieces

[0027] 1) Dry the processed talc at 90-110°C for 2 hours.

[0028] 2) Crushed into 5-40 mesh particles.

[0029] 3) Then in the ozone sterilizer, fill the ozone with a concentration of 54g / m3 in a vacuum state, and sterilize for 35 to 45 minutes while maintaining the air flow at 40Hz.

[0030] 4) Put it in a paper bag and add aluminum foil on the outside.

[0031]5) When using, remove the aluminum foil, put it directly into a 1000ml beaker with a filter paper bag containing 20g of talc, add water at a mass ratio of 1:15, soak for 20min, heat it to boiling in an 800W electric furnace, adjust the power of the electric furnace to 400W, and decoct for 30min , set the volume at 20°C to a 250ml volumetric flask, accurately draw 50ml, evaporate to dryness in a water bath at 60°C, dry at 105°C for 3 hours, put it in a desiccator for 30 minutes, weigh it with an analytical balance, and deco...

Embodiment 2

[0033] Embodiment 2: the preparation method of granular Atractylodes macrocephala Chinese medicine decoction pieces

[0034] 1) Dry the processed Atractylodes macrocephala at 40-60°C until the water content is ≤8.0%.

[0035] 2) Crushed into 5-40 mesh particles.

[0036] 3) Then in the ozone sterilizer, fill the ozone with a concentration of 54g / m3 in a vacuum state, and sterilize for 35 to 45 minutes while maintaining the air flow at 40Hz. Paper packaging→aluminum thin packaging.

[0037] 4) Put it in a paper bag and add aluminum foil on the outside.

[0038] 5) When using, remove the aluminum foil, put the filter paper bag containing 20g Atractylodes macrocephala directly into a 1000ml beaker, add water at a mass ratio of 1:15, soak for 20min, heat it in an 800W electric furnace to boil, adjust the power of the electric furnace to 400W, and decoct for 30min , set the volume at 20°C to a 250ml volumetric flask, accurately draw 50ml, evaporate to dryness in a water bath at ...

Embodiment 3

[0040] Embodiment 3: the preparation method of granular Codonopsis Codonopsis Chinese herbal decoction pieces

[0041] 1) Dry the processed Codonopsis pilosula at 40-60°C until the water content is ≤8.0%.

[0042] 2) Crushed into 5-40 mesh particles.

[0043] 3) Then in the ozone sterilizer, fill the ozone with a concentration of 54g / m3 in a vacuum state, and sterilize for 35 to 45 minutes while maintaining the air flow at 40Hz. Paper packaging→aluminum thin packaging.

[0044] 4) Put it in a paper bag and add aluminum foil on the outside.

[0045] 5) When using, remove the aluminum foil, put a filter paper bag containing 20g Codonopsis pilosula directly into a 1000ml beaker, add water at a mass ratio of 1:15, soak for 20min, heat it in an 800W electric furnace to boil, adjust the power of the electric furnace to 400W, and decoct for 30min , set the volume at 20°C to a 250ml volumetric flask, accurately draw 50ml, evaporate to dryness in a water bath at 60°C, dry at 105°C f...

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PUM

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Abstract

Preparation method for granular Chinese herbal pieces of the invention relates to a preparation method for granular Chinese herbal pieces, comprising the steps of processing, drying and crushing each type of Chinese herbal pieces, sterilizing and packaging. The method of the invention can greatly increase the active ingredient dissolution rate and total decocted substances, thereby increasing the medicine curative effect.

Description

technical field [0001] The invention relates to a preparation method of decoction pieces of traditional Chinese medicine. Background technique [0002] Traditional Chinese medicine is the precious wealth of the Chinese nation. As a unique health resource in our country, it is an important part of our medical system and plays an important role in ensuring people's health. High-efficiency and high-quality traditional Chinese medicine products are the fundamental guarantee for the safety and effectiveness of clinical medication. Chinese medicine decoction pieces are one of the important means of traditional Chinese medicine, but with the improvement of people's drug use level, there are many deficiencies in the use of traditional Chinese medicine decoction pieces in the decoction process, mainly manifested in: [0003] (1) There are obvious regional differences in the traditional usage habits of decoction pieces of traditional Chinese medicine. The processing methods of decoct...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/00A61K35/00A61K36/00A61K9/16
Inventor 黄玉梅孔箭吴志坚卢德明
Owner 广州市药材公司中药饮片厂
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