A kind of medicine for preventing and treating diabetes and its complications and its preparation method

Abstract

The invention relates to a single-herb Chinese medicine of common four-o'clock roots for preventing and treating diabetes and complications thereof, and a preparation method thereof. The single-herb Chinese medicine contains the active components which are extracted from common four-o'clock roots by means of ethanol reflux extraction, reduced pressure concentration and vacuum drying treatment. The pharmacological studies show that the single-herb Chinese medicine has the effects of reducing blood sugar and lipid levels, reducing triglyceride levels in the liver and the skeletal muscles and increasing glycogen levels in the liver and the skeletal muscles, produces hypoglycemic and hypolipidemic effects in both preventative and therapeutic applications, causes no adverse effect on glucose and lipid metabolisms in healthy mice, and can be used for preventing and treating type II diabetes and complications caused thereby. The invention provides a pure natural medicament for the patients suffering from type II diabetes and complications thereof.

Description

technical field [0001] The invention relates to a non-synthetic medicine for preventing and treating type 2 diabetes and its complications, which is prepared from Chinese herbal medicines. Background technique [0002] Diabetes has become the third major disease that seriously endangers human health after tumors and cardiovascular and cerebrovascular diseases. Data from the World Health Organization and the International Diabetes Federation indicate that the total number of diabetic patients in the world will reach 333 million by 2025. According to the results of diabetes census published in 19 provinces and cities in my country, with the increase of average life expectancy, the increase of economic income and the change of lifestyle (such as eating more and moving less, mental stress, smoking and drinking, etc.), the total number of diabetic patients will increase by at least 100 per year. million increased. In the past 20 years, the incidence of diabetes in my country has...

AI Technical Summary

Problems solved by technology

[0005] At present, the oral hypoglycemic drugs approved for use in my country include insulin secretagogues (sulfonylureas, glinides) and non-insulin secretagogues (α-glucosidase inhibitors, biguanides, thiazolidinedione insulin sensitizers) ), but they cannot fundamentally solve the two most significant problems of maintaining long-term efficacy in reducing hyperglycemia and effectively relieving the disease according to the cause. Therefore, finding new therapeutic drugs has always been a research hotspot in this field

Although it has been reported that the single herb Mirabilis root can reduce the blood sugar level of diabetic mice, its extraction method is rough, and the preparation of diabetes models is not classic. And its mechanism has not been reported at home and abroad

In order to further apply Mirabilis root to the prevention and treatment of type 2 diabetes and its complications, there are still many technical problems, including the extraction method of Mirabilis root with low efficacy and stable process, which is often associated with type 2 diabetes. The impact of related symptoms such as tissue glucose and lipid metabolism disorders, as well as the impact on normal people's glucose and lipid metabolism

Images