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Microbial fermentation method for improving active ingredients of schisandra chinensis

A technology of microbial fermentation and Schisandra chinensis, which is applied to medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, pharmaceutical formulas, etc., can solve the problems of shortage of raw materials and low content of active ingredients in Schisandra chinensis, and make up for it The effect of shortage of raw materials and improvement of yield

Inactive Publication Date: 2011-09-21
HEILONGJIANG UNIV
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  • Claims
  • Application Information

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Problems solved by technology

[0004] The present invention aims to solve the current shortage of raw materials of Schisandra chinensis and the low content of active ingredients, and provides a microbial fermentation method for increasing the effective ingredients of Schisandra chinensis

Method used

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  • Microbial fermentation method for improving active ingredients of schisandra chinensis
  • Microbial fermentation method for improving active ingredients of schisandra chinensis
  • Microbial fermentation method for improving active ingredients of schisandra chinensis

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specific Embodiment approach 1

[0009] Embodiment 1: This embodiment improves the microbial fermentation method of the active ingredients of Schisandra chinensis, and is carried out according to the following steps: 1. Pulverize Schisandra chinensis with a pulverizer, and then pass through a 40-mesh sieve to obtain Schisandra chinensis powder; 2. Schisandra chinensis powder Sterile water was added to the saccharomyces cerevisiae, sealed and sterilized at 121°C for 30 minutes to obtain a substrate with a substrate concentration of 0.1-0.8 g / mL; 3. Activating Saccharomyces cerevisiae, adding sterile water to the activated Saccharomyces cerevisiae, Make a concentration of 1 × 10 7 cfu / mL Saccharomyces cerevisiae suspension; 4. Add 1-8 mL of Saccharomyces cerevisiae suspension to 75 mL of the substrate obtained in step 2, then put it into a shaker, and cultivate at 128 r / min and 20 to 36 °C After 11 to 17 days, take out and freeze-dry to obtain fermented Schisandra chinensis.

[0010] Saccharomyces cerevisiae i...

specific Embodiment approach 2

[0011] Embodiment 2: The difference between this embodiment and Embodiment 1 is that the substrate concentration in step 2 is 0.3-0.6 g / mL. Others are the same as the first embodiment.

specific Embodiment approach 3

[0012] Embodiment 3: The difference between this embodiment and Embodiment 1 is that the substrate concentration in step 2 is 0.4-0.5 g / mL. Others are the same as the first embodiment.

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Abstract

The invention relates to a microbial fermentation method for improving active ingredients of schisandra chinensis. The method solves the problems that the conventional schisandra chinensis raw material is short and the content of the active ingredients is low. The method comprises the following steps of: 1, crushing the schisandra chinensis, and screening the crushed schisandra chinensis to obtain schisandra chinensis powder; 2, adding sterile water into the schisandra chinensis powder, sealing and sterilizing to obtain a substrate; 3, activating saccharomyces cerevisiae, and adding sterile water into the activated saccharomyces cerevisiae to form suspension; and 4, adding the suspension into the substrate, then putting the mixture into a shaking bed, culturing, taking out the cultured product, and performing freeze drying on the cultured product to obtain the fermented schisandra chinensis. The schisandra chinensis is fermented by adopting the saccharomyces cerevisiae, so that the rich enzyme system in the microbes is reacted with complex chemical components in the schisandra chinensis, and the active ingredient content of the schisandra chinensis is improved. The method is applied in the field of microbial fermentation of Chinese medicinal herbs.

Description

technical field [0001] The invention relates to a microbial fermentation method for improving the effective components of Schisandra chinensis. Background technique [0002] Schisandra chinensis has the functions of nourishing qi, nourishing the kidney, astringing the lungs, astringent essence, promoting body fluid, quenching thirst, improving intelligence, and calming the nerves. It has the function of strengthening human vision and hearing; it promotes bile secretion and improves antibacterial ability. It is a traditional Chinese medicinal material. Lignans are the main physiologically active substances of Schisandra chinensis and have various physiological functions. There are many kinds of lignans in Schisandra chinensis, mainly schisandrin A, schisandrin A, schisandrin A and schisandrin B. [0003] The three northeastern provinces are the main producing areas of Schisandra chinensis. At present, Schisandra chinensis mainly comes from wild resources. However, due to the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/57
Inventor 郑春英吴桐孙雅北石震华杨鹤岩刘玉洁
Owner HEILONGJIANG UNIV
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