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Application of traditional Chinese medicine composition for preparing drugs for preventing and treating post percutaneous coronary intervention (PCI) no-reflow

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, effective ingredients of hydroxyl compounds, and pharmaceutical formulations, and can solve problems such as undisclosed applications

Inactive Publication Date: 2011-08-10
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above two patents do not disclose the application of the traditional Chinese medicine composition in the prevention and treatment of acute myocardial infarction after PCI without reflow

Method used

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  • Application of traditional Chinese medicine composition for preparing drugs for preventing and treating post percutaneous coronary intervention (PCI) no-reflow
  • Application of traditional Chinese medicine composition for preparing drugs for preventing and treating post percutaneous coronary intervention (PCI) no-reflow
  • Application of traditional Chinese medicine composition for preparing drugs for preventing and treating post percutaneous coronary intervention (PCI) no-reflow

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] a) The raw material drug formula is:

[0047] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense (made) 13.2g

[0048] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 19.8g

[0049] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g;

[0050] b) Crushing process of medicinal materials:

[0051] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 30-40 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0052] c) Extraction concentration and dr...

Embodiment 2

[0058] a) The raw material drug formula is:

[0059] Ginseng 66g Leech 52.8g Wood Beetle 46.2g Frankincense (made) 13.2g

[0060] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 59.4g

[0061] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g

[0062] b) Crushing process of medicinal materials:

[0063] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 70-90 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0064] c) Extraction concentration and dryin...

Embodiment 3

[0069] Embodiment 3: the preparation of pill

[0070] a) The raw material drug formula is:

[0071] Ginseng 39.6g Leech 66g Wood Beetle 46.2g Frankincense (made) 13.2g

[0072] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 46.2g

[0073] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g

[0074] b) Crushing process of medicinal materials:

[0075] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powder after powder is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the powder is 10-20 μm;

[0076] c) Extraction concentration and drying process:

[0077] Add water to extract the volatile oil of Jiangxiang and s...

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Abstract

The invention discloses application of a traditional Chinese medicine composition for preparing drugs for preventing and treating acute myocardial infarction post percutaneous coronary intervention (PCI) no-reflow, wherein the traditional Chinese medicine composition of the invention comprises ginseng, leech, centipede, scorpio, ground beeltle, cicada slough, root of common peony, borneol and the like, and has effects of tonifying qi, invigorating the circulation of blood, eliminating blood stasis and dredging collateral. The clinical study shows that the traditional Chinese medicine composition in the invention can treat and prevent the acute myocardial infarction post PCI no-reflow.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition. Specifically, the invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for preventing and treating acute myocardial infarction without reflow after PCI, which belongs to the field of traditional Chinese medicine applications. Background technique [0002] Acute myocardial infarction (AMI) is dangerous and has a high mortality rate, mainly due to acute thrombotic occlusion of the coronary arteries supplying the myocardium. Therefore, coronary recanalization treatment includes thrombolysis or emergency coronary intervention ( PCI, balloon dilation + stent implantation) is the primary treatment measure to restore coronary blood flow and reperfusion of myocardial tissue [Gersh BJ, Optimal management of acute myocardial infarction at the down of the next millennium.Am Heart J. 1999;138(2pt2):188-202.]. Since t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61P9/10A61K31/045A61K35/62A61K35/64A61K35/646A61K35/648
Inventor 杨跃进吴以岭
Owner HEBEI YILING MEDICINE INST
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