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Chinese medicinal preparation for treating early diabetic nephropathy and preparation method thereof

A technology of diabetic nephropathy and traditional Chinese medicine preparations, which is applied in the direction of medical formulas, urinary system diseases, and medical preparations containing active ingredients, etc., which can solve the problems of poor patient acceptance, high cost, and cost of drug side effects treatment, and achieve the reduction of urinary protein , improve the effect of renal function

Inactive Publication Date: 2012-02-22
傅晓骏 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the method of treating diabetic nephropathy often adopts blood sugar control plus ACEI or ARB, but there are a series of problems in the actual treatment process: such as side effects of drugs and expensive treatment, poor acceptance by patients
These factors have hindered the promotion and application of the above-mentioned treatment methods in society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A traditional Chinese medicine preparation for treating early diabetic nephropathy, which is prepared from the following Chinese herbal medicines in the weight ratio, wherein 10g of leech powder, 60g of astragalus, and 30g of rice kernel root.

[0022] Add the above medicinal materials to 10 times of clear water and decoct together for 60 minutes; then add the filtered medicinal residues to 5 times of clear water for second decoction and decoct for 10 minutes; then add the filtered medicinal residues to 4 times decocting water for three times for 10 minutes; finally, after mixing the water preparations obtained by the first three decoctions, concentrate to 100ml.

Embodiment 2

[0024] A traditional Chinese medicine preparation for treating early diabetic nephropathy, which is prepared from the following Chinese herbal medicines in the weight ratio, wherein 10g of leech powder, 15g of astragalus root, and 50g of rice kernel root.

[0025] Add the above medicinal materials to 8 times of clear water and decoct together for 45 minutes; then add the filtered medicinal residues to 3 times of clear water for second decoction and decoct for 15 minutes; then add the filtered medicinal residues to 5 times decocting water for three times for 15 minutes; finally, after mixing the water preparations obtained by the first three decoctions, concentrate to 100ml.

Embodiment 3

[0027] A traditional Chinese medicine preparation for treating early diabetic nephropathy. The traditional Chinese medicine preparation is prepared from the following Chinese herbal medicines in the weight ratio, wherein leech powder is 10g, astragalus root is 30g, and rice kernel root is 20g. Add the above medicinal materials to 5 times of clear water and decoct together for 30 minutes; then add the filtered medicinal residues to 8 times of clear water for second decoction and decoct for 20 minutes; then add the filtered medicinal residues to 3 times decocted water for three times for 5 minutes; finally, after mixing the water preparations obtained by the first three decoctions, they were concentrated to 100ml.

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Abstract

The invention relates to a Chinese medicinal preparation for treating early diabetic nephropathy and a preparation method thereof, and aims to provide a Chinese medicinal preparation which has an obvious curative effect, low cost, high tolerance and high patient compliance and is safe and reliable and used for treating the early diabetic nephropathy. The Chinese medicinal preparation for treatingthe early diabetic nephropathy comprises astragalus, leech and coix root. The Chinese medicinal preparation can improve the function of kidney, inhibit the activating proliferation of kidney tissue fibroblasts and regulate the release function of inflammation media under the action of tonifying qi, invigorating blood circulation and inducing diuresis, so that pathological links of glomeruli and interstitial fibrosis are blocked by ways of regulating and controlling biological effects of the glomeruli and interstitial cells and the like to prevent and treat renal fibrosis and delay the progress of kidney pathology. Compared with single Chinese patent medicaments, the Chinese medicinal preparation has the characteristics of no obvious toxic or side effect and obvious effects of improving the kidney function and reducing urine protein, and is safe in use.

Description

technical field [0001] The invention relates to a medicine for treating early diabetic nephropathy in clinical medicine, in particular to a traditional Chinese medicine preparation and a preparation method for treating early diabetic nephropathy. Background technique [0002] Diabetic nephropathy refers to chronic complications of diabetes such as diabetic glomerulosclerosis, arteriolar nephrosclerosis, pyelonephritis, and renal papillary necrosis. It is one of the main microvascular complications of diabetes and a common cause of chronic renal failure. Its occurrence begins with the hemodynamic changes of microvessels, that is, glomerulosclerosis characterized by thickening of capillary basement membrane and expansion of mesangial matrix occurs. Diabetes and its complications are increasing rapidly all over the world, and diabetic nephropathy has become the first cause of end-stage renal failure in developed countries. Early detection is the key to reversing the disease. E...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P13/12A61K35/62A61P3/10
Inventor 傅晓骏张婷
Owner 傅晓骏
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