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Intestinal environment-improving agent

A technology of improving agent and internal environment, applied in medical raw materials derived from angiosperms, plant raw materials, food science, etc., to achieve excellent effect of improving intestinal environment

Inactive Publication Date: 2011-06-08
LION CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the other hand, although the immune-stimulating effect and intestinal age score improving effect have been confirmed by ingesting Lactobacillus brevis, a safer and more effective improving agent for improving the intestinal environment is still expected.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～4、 comparative example 1～2

[0047] Components other than shellac were mixed according to the ratio in the following table, and a tablet with a diameter of 9 mm and a weight of 325 mg was prepared. Furthermore, except for Example 4, the tablets were coated with shellac (enteric coating agent) to make enteric-coated tablets. For the identification of lactic acid bacteria, Api 50CHL Biomeriyu One (manufactured by Japan Biomeriu I Co., Ltd.) was used. Determination of the number of viable bacteria Use MRS agar medium for anaerobic culture, and measure the colonies that propagate. In the case of dead bacteria, the value measured using MRS agar medium in the same way as live bacteria was used as the number of dead bacteria before sterilization. The obtained enteric-coated tablets were evaluated as follows. The results are recorded together in the table.

[0048] Thirty men and women who were often constipated were divided into 6 groups of 5, and each took 3 tablets every day from dinner to before going to b...

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Abstract

Disclosed is an agent for improving the intestinal environment, which comprises lactoferrin and a bacterium Lactobacillus brevis as active ingredients.

Description

technical field [0001] The present invention relates to an intestinal environment-improving agent having an excellent intestinal environment-improving effect. Background technique [0002] Symptoms such as poor intake of food or dietary fiber, hormonal imbalance, mental stress caused by disturbing things or the environment, etc., the intestinal environment deteriorates, and the frequency or amount of bowel movements decreases. This deterioration of the intestinal environment may become one of the causes of colorectal cancer or intestinal obstruction. On the other hand, although the immune-stimulating effect and intestinal age score improving effect have been confirmed by ingestion of Lactobacillus brevis, an improving agent that is safer and has an excellent effect of improving the intestinal environment has been desired. [0003] prior art literature [0004] patent documents [0005] Patent Document 1: Japanese Patent Laid-Open No. 2005-068060 [0006] Patent Document ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/74A61K36/18A61K36/81A61K38/16A61P1/00A61P1/14A61P35/00A61P43/00A23L33/00A61K35/747A61K36/67
CPCA61K36/67A61K35/747A61K38/40A61K36/81A61K36/9068A61P1/00A61P1/10A61P1/12A61P1/14A61P35/00A61P43/00A61K2300/00A61K35/74A61K36/18
Inventor 铃木则行森下恭子村越伦明
Owner LION CORP
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